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PDLIM5 PDZ and LIM domain 5 [ Equus asinus (ass) ]

Gene ID: 106830014, updated on 13-Mar-2024

Summary

Gene symbol
PDLIM5
Gene description
PDZ and LIM domain 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
16
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 3 NC_052179.1 (173577200..173773484)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014637388.1 (3678469..3877894, complement)

Chromosome 3 - NC_052179.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123283850 Neighboring gene SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 Neighboring gene hematopoietic prostaglandin D synthase Neighboring gene uncharacterized LOC123283851 Neighboring gene bone morphogenetic protein receptor type 1B Neighboring gene uncharacterized LOC123283853 Neighboring gene unc-5 netrin receptor C

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in muscle structure development IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of filamentous actin IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
PDZ and LIM domain protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052179.1 Reference ASM1607732v2

    Range
    173577200..173773484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044766331.1XP_044622266.1  PDZ and LIM domain protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C4M073
    Conserved Domains (5) summary
    cd09453
    Location:425476
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:484535
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:82396
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:543597
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  2. XM_014839397.2XP_014694883.2  PDZ and LIM domain protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8C4M073
    Conserved Domains (5) summary
    cd09453
    Location:420471
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:479530
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam05109
    Location:85403
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    cl02475
    Location:538592
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  3. XM_044766332.1XP_044622267.1  PDZ and LIM domain protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8C4M073
    Conserved Domains (4) summary
    cd09453
    Location:316367
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    PHA03378
    Location:91315
    PHA03378; EBNA-3B; Provisional
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:434488
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  4. XM_014839400.2XP_014694886.2  PDZ and LIM domain protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8C4M073
    Conserved Domains (3) summary
    cd09453
    Location:311362
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl02475
    Location:429483
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  5. XM_044766334.1XP_044622269.1  PDZ and LIM domain protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A8C4M4R6
    Conserved Domains (1) summary
    cd00992
    Location:1082
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  6. XM_044766333.1XP_044622268.1  PDZ and LIM domain protein 5 isoform X5

    Conserved Domains (3) summary
    cd09453
    Location:303354
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    PHA03378
    Location:59302
    PHA03378; EBNA-3B; Provisional
    cl02475
    Location:421475
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers