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PCK1 phosphoenolpyruvate carboxykinase 1 [ Apteryx mantelli mantelli ]

Gene ID: 106491741, updated on 13-Mar-2024

Summary

Gene symbol
PCK1
Gene description
phosphoenolpyruvate carboxykinase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Apteryx mantelli mantelli (sub-species: mantelli)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Apterygiformes; Apterygidae; Apteryx; Apteryx mantelli
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current AptMant0 (GCF_001039765.1) Unplaced Scaffold NW_014000494.1 (56311..64897, complement)

NW_014000494.1Genomic Context describing neighboring genes Neighboring gene CCCTC-binding factor like Neighboring gene RNA binding motif protein 38

Genomic regions, transcripts, and products

Genomic Sequence:
NW_014000494.1 Unplaced Scaffold Reference AptMant0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase, cytosolic [GTP]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Apteryx australis mantelli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference AptMant0

Genomic

  1. NW_014000494.1 Reference AptMant0

    Range
    56311..64897 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013951404.1XP_013806858.1  phosphoenolpyruvate carboxykinase, cytosolic [GTP]

    UniProtKB/TrEMBL
    A0A8B7JA84
    Conserved Domains (2) summary
    cd00819
    Location:27615
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...
    cl21552
    Location:833
    TPK; Thiamine pyrophosphokinase