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TRIM16 tripartite motif containing 16 [ Homo sapiens (human) ]

Gene ID: 10626, updated on 8-May-2016
Official Symbol
TRIM16provided by HGNC
Official Full Name
tripartite motif containing 16provided by HGNC
Primary source
HGNC:HGNC:17241
See related
Ensembl:ENSG00000221926 HPRD:15552; MIM:609505; Vega:OTTHUMG00000059067
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EBBP
Summary
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008]
Orthologs
Location:
17p11.2
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 17 NC_000017.11 (15627966..15682879, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15531277..15587625, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene TVP23C-CDRT4 readthrough Neighboring gene peptidylprolyl isomerase A (cyclophilin A) pseudogene Neighboring gene trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) Neighboring gene CMT1A duplicated region transcript 1 Neighboring gene zinc finger protein 29, pseudogene Neighboring gene zinc finger protein 286A Neighboring gene ubiquitin conjugating enzyme E2 S pseudogene 1 Neighboring gene uncharacterized LOC105371559 Neighboring gene TBC1 domain family member 26

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Potential readthrough

Included gene: CDRT1

Homology

Clone Names

  • DKFZp434O1826

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
NACHT domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
interleukin-1 binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
PML body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
tripartite motif-containing protein 16
Names
estrogen-responsive B box protein
tripartite motif-containing 16

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006470.3NP_006461.3  tripartite motif-containing protein 16

    See identical proteins and their annotated locations for NP_006461.3

    Status: REVIEWED

    Source sequence(s)
    BC001564, BC067096
    Consensus CDS
    CCDS11171.1
    UniProtKB/Swiss-Prot
    O95361
    Related
    ENSP00000338989, ENST00000336708
    Conserved Domains (2) summary
    COG5143
    Location:264391
    SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]
    cd12890
    Location:375547
    SPRY_PRY_TRIM16; PRY/SPRY domain in tripartite motif-containing protein 16 (TRIM16)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p2 Primary Assembly

    Range
    15627966..15682879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018928.2 Alternate CHM1_1.1

    Range
    15540352..15595047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)