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POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) [ Homo sapiens (human) ]

Gene ID: 10623, updated on 7-Dec-2014
Official Symbol
POLR3Cprovided by HGNC
Official Full Name
polymerase (RNA) III (DNA directed) polypeptide C (62kD)provided by HGNC
Primary source
HGNC:HGNC:30076
See related
Ensembl:ENSG00000186141; HPRD:17880; Vega:OTTHUMG00000013753
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RPC3; RPC62
See POLR3C in Epigenomics, MapViewer
Location:
1q21.1
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 1 NC_000001.11 (145824141..145842505)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145592605..145610972, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene CD160 molecule Neighboring gene ring finger protein 115 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 17 Neighboring gene microRNA 6736 Neighboring gene protein inhibitor of activated STAT, 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat upregulates the transcription by RNA polymerase III of co-transfected or endogenous cellular Alu-repeated sequences by activating transcription factor TFIIIC PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-directed RNA polymerase activity TAS
Traceable Author Statement
more info
PubMed 
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
DNA-directed RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
 
DNA-directed RNA polymerase III complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
DNA-directed RNA polymerase III subunit RPC3
Names
DNA-directed RNA polymerase III subunit RPC3
RNA polymerase III subunit C3
RNA polymerase III 62 kDa subunit
DNA-directed III 62 kDa polypeptide
DNA-directed RNA polymerase III subunit C

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006468.6NP_006459.3  DNA-directed RNA polymerase III subunit RPC3

    See proteins identical to NP_006459.3

    Status: PROVISIONAL

    Source sequence(s)
    BC002586
    Consensus CDS
    CCDS72864.1
    UniProtKB/TrEMBL
    A0A024R4C1
    UniProtKB/Swiss-Prot
    Q9BUI4
    Related
    ENSP00000334564, OTTHUMP00000015591, ENST00000334163, OTTHUMT00000038542
    Conserved Domains (2) summary
    pfam08221
    Location:768
    HTH_9; RNA polymerase III subunit RPC82 helix-turn-helix domain
    pfam05645
    Location:146345
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000001.11 

    Range
    145824141..145842505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005272927.1XP_005272984.1  

    See proteins identical to XP_005272984.1

    Conserved Domains (1) summary
    pfam05645
    Location:29228
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82
  2. XM_005277333.2XP_005277390.1  

    Conserved Domains (2) summary
    pfam08221
    Location:2081
    HTH_9; RNA polymerase III subunit RPC82 helix-turn-helix domain
    pfam05645
    Location:159358
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82
  3. XM_005272928.1XP_005272985.1  

    See proteins identical to XP_005272985.1

    Conserved Domains (1) summary
    pfam05645
    Location:29228
    RNA_pol_Rpc82; RNA polymerase III subunit RPC82

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 

    Range
    147192355..147210631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000133.1 

    Range
    119556179..119574446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)