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Fbxo4 F-box protein 4 [ Mus musculus (house mouse) ]

Gene ID: 106052, updated on 3-Jul-2016
Official Symbol
Fbxo4provided by MGI
Official Full Name
F-box protein 4provided by MGI
Primary source
MGI:MGI:2146220
See related
Ensembl:ENSMUSG00000022184 Vega:OTTMUSG00000027965
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fbx4; AI851261; AW494535; 1700096C12Rik
Orthologs
Location:
15; 15 A1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (3963564..3979573, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (3913564..3929573, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene exportin 4 pseudogene Neighboring gene expressed sequence AW549877 Neighboring gene uncharacterized A630020A06

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to ionizing radiation IDA
Inferred from Direct Assay
more info
PubMed 
common myeloid progenitor cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of fibroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of protein localization to nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein polyubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
posttranscriptional regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein destabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein polyubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
regulation of DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
SCF ubiquitin ligase complex IDA
Inferred from Direct Assay
more info
PubMed 
SCF ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134099.2NP_598860.2  F-box only protein 4

    See identical proteins and their annotated locations for NP_598860.2

    Status: VALIDATED

    Source sequence(s)
    AC137902, AI480454, BC036385
    Consensus CDS
    CCDS27359.1
    UniProtKB/Swiss-Prot
    Q8CHQ0
    Related
    ENSMUSP00000022791, OTTMUSP00000035163, ENSMUST00000022791, OTTMUST00000069277
    Conserved Domains (2) summary
    cd11656
    Location:160382
    FBX4_GTPase_like; C-terminal GTPase-like domain of F-Box Only Protein 4
    pfam12937
    Location:57103
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    3963564..3979573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)