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Prickle1 prickle planar cell polarity protein 1 [ Mus musculus (house mouse) ]

Gene ID: 106042, updated on 28-May-2016
Official Symbol
Prickle1provided by MGI
Official Full Name
prickle planar cell polarity protein 1provided by MGI
Primary source
MGI:MGI:1916034
See related
Ensembl:ENSMUSG00000036158 Vega:OTTMUSG00000021009
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mpk1; Prickle; AW215793; b2b019Clo; 1110058P22Rik
Orthologs
Location:
15; 15 E3
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (93499111..93596266, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (93329545..93426322, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41384 Neighboring gene zinc finger CCHC-type and RNA binding motif 1 Neighboring gene periphilin 1 Neighboring gene predicted gene, 30181 Neighboring gene predicted gene, 41385 Neighboring gene predicted gene, 41387 Neighboring gene predicted gene, 30279

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
aorta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
coronary vasculature development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cardiac muscle cell myoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
neural tube closure ISO
Inferred from Sequence Orthology
more info
 
positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein import into nucleus ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
prickle-like protein 1
Names
prickle homolog 1
prickle like 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033217.4NP_001028389.1  prickle-like protein 1

    See identical proteins and their annotated locations for NP_001028389.1

    Status: PROVISIONAL

    Source sequence(s)
    AC124592, AC126556
    Consensus CDS
    CCDS27769.1
    UniProtKB/Swiss-Prot
    Q3U5C7
    Related
    ENSMUSP00000049204, OTTMUSP00000023048, ENSMUST00000048982, OTTMUST00000049663
    Conserved Domains (4) summary
    cd09418
    Location:189244
    LIM2_Prickle; The second LIM domain of Prickle
    cd09420
    Location:249307
    LIM3_Prickle; The third LIM domain of Prickle
    cd09483
    Location:126184
    LIM1_Prickle_1; The first LIM domain of Prickle 1
    cd09827
    Location:22118
    PET_Prickle; The PET domain of Prickle

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    93499111..93596266 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006520265.1XP_006520328.1  

    See identical proteins and their annotated locations for XP_006520328.1

    UniProtKB/Swiss-Prot
    Q3U5C7
    Conserved Domains (4) summary
    cd09418
    Location:189244
    LIM2_Prickle; The second LIM domain of Prickle
    cd09420
    Location:249307
    LIM3_Prickle; The third LIM domain of Prickle
    cd09483
    Location:126184
    LIM1_Prickle_1; The first LIM domain of Prickle 1
    cd09827
    Location:22118
    PET_Prickle; The PET domain of Prickle
  2. XM_006520266.2XP_006520329.1  

    See identical proteins and their annotated locations for XP_006520329.1

    UniProtKB/Swiss-Prot
    Q3U5C7
    Related
    ENSMUSP00000104878, OTTMUSP00000023049, ENSMUST00000109255, OTTMUST00000049664
    Conserved Domains (4) summary
    cd09418
    Location:189244
    LIM2_Prickle; The second LIM domain of Prickle
    cd09420
    Location:249307
    LIM3_Prickle; The third LIM domain of Prickle
    cd09483
    Location:126184
    LIM1_Prickle_1; The first LIM domain of Prickle 1
    cd09827
    Location:22118
    PET_Prickle; The PET domain of Prickle
  3. XM_006520264.2XP_006520327.1  

    See identical proteins and their annotated locations for XP_006520327.1

    UniProtKB/Swiss-Prot
    Q3U5C7
    Conserved Domains (4) summary
    cd09418
    Location:189244
    LIM2_Prickle; The second LIM domain of Prickle
    cd09420
    Location:249307
    LIM3_Prickle; The third LIM domain of Prickle
    cd09483
    Location:126184
    LIM1_Prickle_1; The first LIM domain of Prickle 1
    cd09827
    Location:22118
    PET_Prickle; The PET domain of Prickle

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    95647051..95744081 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)