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Iqgap2 IQ motif containing GTPase activating protein 2 [ Dipodomys ordii (Ord's kangaroo rat) ]

Gene ID: 105992379, updated on 13-Mar-2024

Summary

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Gene symbol
Iqgap2
Gene description
IQ motif containing GTPase activating protein 2
See related
Ensembl:ENSDORG00000006829
Gene type
protein coding
RefSeq status
MODEL
Organism
Dipodomys ordii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae; Dipodomyinae; Dipodomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
100 current Dord_2.0 (GCF_000151885.1) Unplaced Scaffold NW_012267299.1 (2799066..3055552)

NW_012267299.1Genomic Context describing neighboring genes Neighboring gene POC5 centriolar protein Neighboring gene synaptic vesicle glycoprotein 2C Neighboring gene coagulation factor II thrombin receptor like 2 Neighboring gene deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial pseudogene Neighboring gene coagulation factor II thrombin receptor

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012267299.1 Unplaced Scaffold Reference Dord_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating-like protein IQGAP2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dipodomys ordii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Dord_2.0

Genomic

  1. NW_012267299.1 Reference Dord_2.0

    Range
    2799066..3055552
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013025233.1 → XP_012880687.1  ras GTPase-activating-like protein IQGAP2

    UniProtKB/TrEMBL
    A0A1S3FXX0
    Related
    ENSDORP00000006399.2, ENSDORT00000006830.2
    Conserved Domains (5) summary
    smart00456
    Location:577 → 604
    WW; Domain with 2 conserved Trp (W) residues
    smart00323
    Location:881 → 1233
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:42 → 156
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam03836
    Location:1342 → 1473
    RasGAP_C; RasGAP C-terminus
    cl02569
    Location:892 → 1250
    RasGAP; Ras GTPase Activating Domain
Nucleotide Protein
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