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LOC105916189 rho GTPase-activating protein 8 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105916189, updated on 25-Jan-2024

Summary

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Gene symbol
LOC105916189
Gene description
rho GTPase-activating protein 8
See related
Ensembl:ENSFHEG00000023240
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Also known as
arhgap8
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Genomic context

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Location:
chromosome: 17
Exon count:
13
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 17 NC_046377.1 (20682825..20696424)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012224569.1 (200118..216091, complement)

Chromosome 17 - NC_046377.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110366728 Neighboring gene potassium voltage-gated channel, shaker-related subfamily, member 1b Neighboring gene shaker-related potassium channel tsha2 Neighboring gene uncharacterized LOC110366727 Neighboring gene PHD finger protein 21B Neighboring gene uncharacterized LOC110366726

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endocytic recycling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 8
Names
BCH domain-containing Cdc42GAP-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046377.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    20682825..20696424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036149031.1 → XP_036004924.1  rho GTPase-activating protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2UR69
    Conserved Domains (2) summary
    cd00170
    Location:52 → 185
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl02570
    Location:221 → 412
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  2. XM_036149029.1 → XP_036004922.1  rho GTPase-activating protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2UR69
    Conserved Domains (2) summary
    cd00170
    Location:52 → 185
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl02570
    Location:221 → 412
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  3. XM_021309532.2 → XP_021165207.2  rho GTPase-activating protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2UR69
    Conserved Domains (2) summary
    cd00170
    Location:84 → 217
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl02570
    Location:253 → 444
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...

  4. XM_036149030.1 → XP_036004923.1  rho GTPase-activating protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2UR69
    Conserved Domains (2) summary
    cd00170
    Location:52 → 185
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl02570
    Location:221 → 412
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
Nucleotide Protein
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