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LNPEP leucyl and cystinyl aminopeptidase [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105876112, updated on 13-Mar-2024

Summary

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Gene symbol
LNPEP
Gene description
leucyl and cystinyl aminopeptidase
See related
Ensembl:ENSMICG00000046342
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See LNPEP in Genome Data Viewer
Location:
chromosome: 12
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 12 NC_033671.1 (83080056..83167125, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195043.1 (5078010..5165077, complement)

Chromosome 12 - NC_033671.1Genomic Context describing neighboring genes Neighboring gene RIO kinase 2 Neighboring gene 2'-5'-oligoadenylate synthase 1-like Neighboring gene limb and CNS expressed 1 Neighboring gene endoplasmic reticulum aminopeptidase 2 Neighboring gene endoplasmic reticulum aminopeptidase 1 Neighboring gene calpastatin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloaminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucyl-cystinyl aminopeptidase
Names
leucyl/cystinyl aminopeptidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033671.1 Reference Mmur_3.0 Primary Assembly

    Range
    83080056..83167125 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012773726.1 → XP_012629180.1  leucyl-cystinyl aminopeptidase isoform X1

    UniProtKB/TrEMBL
    A0A8C5Y2F2
    Related
    ENSMICP00000044505.1, ENSMICT00000064081.1
    Conserved Domains (3) summary
    cd09601
    Location:175 → 617
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    pfam01433
    Location:167 → 552
    Peptidase_M1; Peptidase family M1
    pfam11838
    Location:690 → 1005
    ERAP1_C; ERAP1-like C-terminal domain

  2. XM_012773747.2 → XP_012629201.1  leucyl-cystinyl aminopeptidase isoform X2

    See identical proteins and their annotated locations for XP_012629201.1

    UniProtKB/TrEMBL
    A0A8B7GZN6
    Conserved Domains (3) summary
    cd09601
    Location:161 → 603
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    pfam01433
    Location:153 → 538
    Peptidase_M1; Peptidase family M1
    pfam11838
    Location:676 → 991
    ERAP1_C; ERAP1-like C-terminal domain

  3. XM_012773735.2 → XP_012629189.1  leucyl-cystinyl aminopeptidase isoform X2

    See identical proteins and their annotated locations for XP_012629189.1

    UniProtKB/TrEMBL
    A0A8B7GZN6
    Conserved Domains (3) summary
    cd09601
    Location:161 → 603
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    pfam01433
    Location:153 → 538
    Peptidase_M1; Peptidase family M1
    pfam11838
    Location:676 → 991
    ERAP1_C; ERAP1-like C-terminal domain

  4. XM_012773742.2 → XP_012629196.1  leucyl-cystinyl aminopeptidase isoform X2

    See identical proteins and their annotated locations for XP_012629196.1

    UniProtKB/TrEMBL
    A0A8B7GZN6
    Conserved Domains (3) summary
    cd09601
    Location:161 → 603
    M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)
    pfam01433
    Location:153 → 538
    Peptidase_M1; Peptidase family M1
    pfam11838
    Location:676 → 991
    ERAP1_C; ERAP1-like C-terminal domain
Nucleotide Protein
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