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NPR2 natriuretic peptide receptor 2 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105874299, updated on 13-Mar-2024

Summary

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Gene symbol
NPR2
Gene description
natriuretic peptide receptor 2
See related
Ensembl:ENSMICG00000002555
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
23
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 10 NC_033669.1 (68763216..68780276)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012196341.1 (795107..812165, complement)

Chromosome 10 - NC_033669.1Genomic Context describing neighboring genes Neighboring gene cAMP responsive element binding protein 3 Neighboring gene glucosylceramidase beta 2 Neighboring gene RGP1 homolog, RAB6A GEF complex partner 1 Neighboring gene microseminoprotein, prostate associated Neighboring gene sperm associated antigen 8 Neighboring gene histidine triad nucleotide binding protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables natriuretic peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor guanylyl cyclase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
atrial natriuretic peptide receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033669.1 Reference Mmur_3.0 Primary Assembly

    Range
    68763216..68780276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012769990.2 → XP_012625444.1  atrial natriuretic peptide receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8B7GQQ5
    Conserved Domains (6) summary
    smart00044
    Location:827 → 1011
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:520 → 794
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam00211
    Location:854 → 1038
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam01094
    Location:46 → 399
    ANF_receptor; Receptor family ligand binding region
    pfam07701
    Location:803 → 848
    HNOBA; Heme NO binding associated
    cl10011
    Location:28 → 423
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

  2. XM_020289410.1 → XP_020144999.1  atrial natriuretic peptide receptor 2 isoform X3

    UniProtKB/TrEMBL
    A0A8B7XBY2
    Conserved Domains (4) summary
    smart00044
    Location:802 → 986
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:488 → 769
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam07701
    Location:778 → 823
    HNOBA; Heme NO binding associated
    cl10011
    Location:28 → 423
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

  3. XM_020289411.1 → XP_020145000.1  atrial natriuretic peptide receptor 2 isoform X5

    UniProtKB/TrEMBL
    A0A8B7XCT5
    Conserved Domains (4) summary
    cd14042
    Location:520 → 794
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam07701
    Location:803 → 848
    HNOBA; Heme NO binding associated
    cl10011
    Location:28 → 423
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
    cl27308
    Location:827 → 906
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain

  4. XM_012769992.2 → XP_012625446.1  atrial natriuretic peptide receptor 2 isoform X4

    UniProtKB/TrEMBL
    A0A8B7GQV1
    Conserved Domains (6) summary
    smart00044
    Location:802 → 986
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:488 → 769
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam00211
    Location:829 → 1015
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam01094
    Location:46 → 399
    ANF_receptor; Receptor family ligand binding region
    pfam07701
    Location:778 → 823
    HNOBA; Heme NO binding associated
    cl10011
    Location:28 → 423
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

  5. XM_012769991.2 → XP_012625445.1  atrial natriuretic peptide receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8B7GS13
    Related
    ENSMICP00000002335.3, ENSMICT00000002558.3
    Conserved Domains (6) summary
    smart00044
    Location:827 → 1011
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:520 → 794
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam00211
    Location:854 → 1040
    Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
    pfam01094
    Location:46 → 399
    ANF_receptor; Receptor family ligand binding region
    pfam07701
    Location:803 → 848
    HNOBA; Heme NO binding associated
    cl10011
    Location:28 → 423
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version

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