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DARS2 aspartyl-tRNA synthetase 2, mitochondrial [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105871698, updated on 13-Mar-2024

Summary

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Gene symbol
DARS2
Gene description
aspartyl-tRNA synthetase 2, mitochondrial
See related
Ensembl:ENSMICG00000002969
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 2 NC_033661.1 (134967988..134995909)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195886.1 (3812399..3840349, complement)

Chromosome 2 - NC_033661.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 20 Neighboring gene histidine triad nucleotide-binding protein 1 pseudogene Neighboring gene centromere protein L Neighboring gene uncharacterized LOC105871650 Neighboring gene zinc finger and BTB domain containing 37 Neighboring gene serpin family C member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aspartate-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aspartyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aspartate--tRNA ligase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033661.1 Reference Mmur_3.0 Primary Assembly

    Range
    134967988..134995909
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012765174.2 → XP_012620628.1  aspartate--tRNA ligase, mitochondrial

    UniProtKB/TrEMBL
    A0A8B7GE05, A0A8C5UUL3
    Related
    ENSMICP00000002707.2, ENSMICT00000002974.3
    Conserved Domains (4) summary
    PRK00476
    Location:49 → 646
    aspS; aspartyl-tRNA synthetase; Validated
    cd04317
    Location:49 → 182
    EcAspRS_like_N; EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND) ...
    pfam02938
    Location:372 → 462
    GAD; GAD domain
    cl00268
    Location:186 → 619
    class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
Nucleotide Protein
Heading Accession and Version

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