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DEPTOR DEP domain containing MTOR interacting protein [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105865324, updated on 13-Mar-2024

Summary

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Gene symbol
DEPTOR
Gene description
DEP domain containing MTOR interacting protein
See related
Ensembl:ENSMICG00000017305
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 9 NC_033668.1 (60678941..60867241, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012202841.1 (1175094..1363328)

Chromosome 9 - NC_033668.1Genomic Context describing neighboring genes Neighboring gene MDM2 binding protein Neighboring gene mitochondrial ribosomal protein L13 Neighboring gene collagen type XIV alpha 1 chain Neighboring gene DNA replication and sister chromatid cohesion 1 Neighboring gene TATA-box binding protein associated factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DEP domain-containing mTOR-interacting protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033668.1 Reference Mmur_3.0 Primary Assembly

    Range
    60678941..60867241 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012753798.2 → XP_012609252.1  DEP domain-containing mTOR-interacting protein isoform X2

    See identical proteins and their annotated locations for XP_012609252.1

    UniProtKB/TrEMBL
    A0A8C5V8M3, A0A8C5Y0L0
    Related
    ENSMICP00000032044.2, ENSMICT00000048356.2
    Conserved Domains (3) summary
    cd00992
    Location:345 → 409
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04441
    Location:139 → 223
    DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
    cd04442
    Location:42 → 123
    DEP_1_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.

  2. XM_012753797.2 → XP_012609251.1  DEP domain-containing mTOR-interacting protein isoform X1

    See identical proteins and their annotated locations for XP_012609251.1

    UniProtKB/TrEMBL
    A0A8C5V8M3, A0A8C5Y0L0
    Related
    ENSMICP00000044082.1, ENSMICT00000068278.1
    Conserved Domains (3) summary
    cd00992
    Location:345 → 409
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04441
    Location:139 → 223
    DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
    cd04442
    Location:42 → 123
    DEP_1_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.

  3. XM_012753800.2 → XP_012609254.1  DEP domain-containing mTOR-interacting protein isoform X3

    UniProtKB/TrEMBL
    A0A8B7FKP9, A0A8C5V8M3
    Conserved Domains (3) summary
    cd00992
    Location:310 → 374
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04441
    Location:104 → 188
    DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
    cl02442
    Location:13 → 88
    DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
Nucleotide Protein
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