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SREBF1 sterol regulatory element binding transcription factor 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105861966, updated on 13-Mar-2024

Summary

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Gene symbol
SREBF1
Gene description
sterol regulatory element binding transcription factor 1
See related
Ensembl:ENSMICG00000012535
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
20
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 16 NC_033675.1 (59811470..59834905, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012201241.1 (4286181..4309708)

Chromosome 16 - NC_033675.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105862024 Neighboring gene retinoic acid induced 1 Neighboring gene uncharacterized LOC105861967 Neighboring gene target of myb1 like 2 membrane trafficking protein Neighboring gene dynein regulatory complex subunit 3 Neighboring gene ATP synthase mitochondrial F1 complex assembly factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol regulatory element-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033675.1 Reference Mmur_3.0 Primary Assembly

    Range
    59811470..59834905 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020281196.1 → XP_020136785.1  sterol regulatory element-binding protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8B7WPL0
    Related
    ENSMICP00000016374.2, ENSMICT00000035664.2
    Conserved Domains (2) summary
    cd00083
    Location:357 → 414
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl27975
    Location:75 → 260
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  2. XM_012747911.2 → XP_012603365.2  sterol regulatory element-binding protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8B7F6E1
    Related
    ENSMICP00000011425.3, ENSMICT00000012544.3
    Conserved Domains (2) summary
    cd00083
    Location:326 → 383
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cl27975
    Location:44 → 229
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  3. XM_012747910.1 → XP_012603364.1  sterol regulatory element-binding protein 1 isoform X2

    See identical proteins and their annotated locations for XP_012603364.1

    UniProtKB/TrEMBL
    A0A8B7F6J2
    Conserved Domains (3) summary
    cd00083
    Location:302 → 359
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11235
    Location:65 → 214
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam16665
    Location:39 → 145
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
Nucleotide Protein
Heading Accession and Version

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