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SMAD3 SMAD family member 3 [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105821424, updated on 13-Mar-2024

Summary

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Gene symbol
SMAD3
Gene description
SMAD family member 3
See related
Ensembl:ENSPCOG00000023000
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012151652.1 (50709..160840)

NW_012151652.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105821425 Neighboring gene alpha and gamma adaptin binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012151652.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables I-SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heteromeric SMAD protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mothers against decapentaplegic homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012151652.1 Reference Pcoq_1.0 Primary Assembly

    Range
    50709..160840
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012658127.1 → XP_012513581.1  mothers against decapentaplegic homolog 3 isoform X2

    See identical proteins and their annotated locations for XP_012513581.1

    UniProtKB/TrEMBL
    A0A2K6G6P5, A0A2K6G6P7
    Related
    ENSPCOP00000021904.1, ENSPCOT00000032574.1
    Conserved Domains (2) summary
    cd10491
    Location:8 → 132
    MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
    cd10985
    Location:224 → 414
    MH2_SMAD_2_3; C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3

  2. XM_012658126.1 → XP_012513580.1  mothers against decapentaplegic homolog 3 isoform X1

    UniProtKB/TrEMBL
    A0A2K6G6P7
    Conserved Domains (2) summary
    cd10491
    Location:8 → 132
    MH1_SMAD_2_3; N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3
    cl00056
    Location:224 → 385
    MH2; C-terminal Mad Homology 2 (MH2) domain
Nucleotide Protein
Heading Accession and Version

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