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CFTR CF transmembrane conductance regulator [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105817115, updated on 13-Mar-2024

Summary

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Gene symbol
CFTR
Gene description
CF transmembrane conductance regulator
See related
Ensembl:ENSPCOG00000014929
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See CFTR in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012149729.1 (7274661..7416420, complement)

NW_012149729.1Genomic Context describing neighboring genes Neighboring gene developmental pluripotency-associated protein 4 pseudogene Neighboring gene cortactin binding protein 2 Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1 Neighboring gene Wnt family member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012149729.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bicarbonate transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cystic fibrosis transmembrane conductance regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012149729.1 Reference Pcoq_1.0 Primary Assembly

    Range
    7274661..7416420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012652736.1 → XP_012508190.1  cystic fibrosis transmembrane conductance regulator

    UniProtKB/TrEMBL
    A0A2K6F053
    Related
    ENSPCOP00000007376.1, ENSPCOT00000017919.1
    Conserved Domains (6) summary
    cd03289
    Location:1185 → 1445
    ABCC_CFTR2; ATP-binding cassette domain 2 of CFTR,subfamily C
    cd03291
    Location:403 → 684
    ABCC_CFTR1; ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C
    TIGR01271
    Location:27 → 1445
    CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
    pfam00664
    Location:99 → 317
    ABC_membrane; ABC transporter transmembrane region
    pfam14396
    Location:653 → 863
    CFTR_R; Cystic fibrosis TM conductance regulator (CFTR), regulator domain
    cl00549
    Location:880 → 1092
    ABC_membrane; ABC transporter transmembrane region
Nucleotide Protein
Heading Accession and Version

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