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ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105806748, updated on 13-Mar-2024

Summary

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Gene symbol
ASAP2
Gene description
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
See related
Ensembl:ENSPCOG00000019755
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012138858.1 (400430..593897, complement)

NW_012138858.1Genomic Context describing neighboring genes Neighboring gene cleavage and polyadenylation specific factor 3 Neighboring gene integrin subunit beta 1 binding protein 1 Neighboring gene 26S proteasome non-ATPase regulatory subunit 7 pseudogene Neighboring gene lysine--tRNA ligase-like Neighboring gene membrane bound O-acyltransferase domain containing 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012138858.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012138858.1 Reference Pcoq_1.0 Primary Assembly

    Range
    400430..593897 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012639955.1 → XP_012495409.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A2K6FPW7, A0A2K6FPX0
    Related
    ENSPCOP00000016013.1, ENSPCOT00000026635.1
    Conserved Domains (8) summary
    cd07642
    Location:34 → 248
    BAR_ASAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 2
    cd11966
    Location:948 → 1003
    SH3_ASAP2; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 2
    cd00204
    Location:579 → 673
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:297 → 403
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    pfam00169
    Location:306 → 393
    PH; PH domain
    pfam01412
    Location:421 → 538
    ArfGap; Putative GTPase activating protein for Arf
    pfam13857
    Location:607 → 661
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:586 → 618
    ANK; ANK repeat [structural motif]

  2. XM_012639956.1 → XP_012495410.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A2K6FPW5, A0A2K6FPW7
    Related
    ENSPCOP00000016014.1, ENSPCOT00000026636.1
    Conserved Domains (8) summary
    cd07642
    Location:34 → 248
    BAR_ASAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 2
    cd11966
    Location:903 → 958
    SH3_ASAP2; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 2
    cd00204
    Location:579 → 673
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:297 → 403
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    pfam00169
    Location:306 → 393
    PH; PH domain
    pfam01412
    Location:421 → 538
    ArfGap; Putative GTPase activating protein for Arf
    pfam13857
    Location:607 → 661
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:586 → 618
    ANK; ANK repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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