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TNKS tankyrase [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105728399, updated on 19-Apr-2024

Summary

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Gene symbol
TNKS
Gene description
tankyrase
See related
Ensembl:ENSANAG00000022197
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988494.1 (9625106..9833919, complement)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018509166.1 (712605..914779)

NW_026988494.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105728403 Neighboring gene large ribosomal subunit protein uL22-like Neighboring gene dual specificity phosphatase 4 Neighboring gene uncharacterized LOC135271457 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC135271462

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ ADP-ribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein localization to ciliary inversin compartment IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in ciliary inversin compartment IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
poly [ADP-ribose] polymerase tankyrase-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988494.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    9625106..9833919 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012468767.3 → XP_012324190.1  poly [ADP-ribose] polymerase tankyrase-1

    UniProtKB/TrEMBL
    A0A2K5CIV3, A0A2K5CIX8
    Related
    ENSANAP00000008614.1
    Conserved Domains (8) summary
    cd09524
    Location:1024 → 1087
    SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily
    smart00454
    Location:1028 → 1085
    SAM; Sterile alpha motif
    cd00204
    Location:674 → 799
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd01438
    Location:1089 → 1311
    tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...
    pfam00644
    Location:1103 → 1306
    PARP; Poly(ADP-ribose) polymerase catalytic domain
    pfam12796
    Location:686 → 778
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:801 → 855
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:369 → 397
    ANK; ANK repeat [structural motif]
Nucleotide Protein
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