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IKBKG inhibitor of nuclear factor kappa B kinase regulatory subunit gamma [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105727270, updated on 12-Apr-2024

Summary

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Gene symbol
IKBKG
Gene description
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
See related
Ensembl:ENSANAG00000032209
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988553.1 (3044265..3075502)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018512810.1 (837386..869287, complement)

NW_026988553.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 10 member 3 Neighboring gene FAM3 metabolism regulating signaling molecule A Neighboring gene glucose-6-phosphate dehydrogenase Neighboring gene RNA-binding protein 7-like Neighboring gene GRB2 associated binding protein 3 Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene dyskerin pseudouridine synthase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of IkappaB kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NF-kappa-B essential modulator
Names
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
inhibitor of nuclear factor kappa B kinase subunit gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988553.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    3044265..3075502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012467062.3 → XP_012322485.1  NF-kappa-B essential modulator isoform X1

    See identical proteins and their annotated locations for XP_012322485.1

    UniProtKB/TrEMBL
    A0A2K5E6P3, A0A2K5E6Q1
    Conserved Domains (3) summary
    pfam11577
    Location:44 → 111
    NEMO; NF-kappa-B essential modulator NEMO
    pfam16516
    Location:259 → 344
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
    cl00459
    Location:179 → 287
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily

  2. XM_012467063.3 → XP_012322486.1  NF-kappa-B essential modulator isoform X1

    See identical proteins and their annotated locations for XP_012322486.1

    UniProtKB/TrEMBL
    A0A2K5E6P3, A0A2K5E6Q1
    Conserved Domains (3) summary
    pfam11577
    Location:44 → 111
    NEMO; NF-kappa-B essential modulator NEMO
    pfam16516
    Location:259 → 344
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
    cl00459
    Location:179 → 287
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily

  3. XM_021668831.2 → XP_021524506.1  NF-kappa-B essential modulator isoform X3

    Conserved Domains (2) summary
    pfam16516
    Location:189 → 274
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
    cl25732
    Location:1 → 226
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_012467061.3 → XP_012322484.1  NF-kappa-B essential modulator isoform X1

    See identical proteins and their annotated locations for XP_012322484.1

    UniProtKB/TrEMBL
    A0A2K5E6P3, A0A2K5E6Q1
    Related
    ENSANAP00000028829.1
    Conserved Domains (3) summary
    pfam11577
    Location:44 → 111
    NEMO; NF-kappa-B essential modulator NEMO
    pfam16516
    Location:259 → 344
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
    cl00459
    Location:179 → 287
    MIT_CorA-like; metal ion transporter CorA-like divalent cation transporter superfamily

  5. XM_012467064.3 → XP_012322487.1  NF-kappa-B essential modulator isoform X2

    Conserved Domains (2) summary
    pfam11577
    Location:44 → 111
    NEMO; NF-kappa-B essential modulator NEMO
    pfam16516
    Location:259 → 344
    CC2-LZ; Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator

RNA

  1. XR_001109737.3 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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