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AIFM3 apoptosis inducing factor mitochondria associated 3 [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105726925, updated on 15-Apr-2024

Summary

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Gene symbol
AIFM3
Gene description
apoptosis inducing factor mitochondria associated 3
See related
Ensembl:ENSANAG00000033300
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988625.1 (184554..198156, complement)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018508548.1 (103076..119314, complement)

NW_026988625.1Genomic Context describing neighboring genes Neighboring gene THAP domain containing 7 Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene CRK like proto-oncogene, adaptor protein Neighboring gene ferritin heavy chain-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on NAD(P)H IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptosis-inducing factor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988625.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    184554..198156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064371886.1 → XP_064227956.1  apoptosis-inducing factor 3 isoform X2

  2. XM_012466514.2 → XP_012321937.1  apoptosis-inducing factor 3 isoform X3

    UniProtKB/TrEMBL
    A0A2K5EEF0
    Conserved Domains (5) summary
    cd03478
    Location:70 → 156
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:319 → 399
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:180 → 478
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:497 → 547
    Reductase_C; Reductase C-terminal
    cl21454
    Location:181 → 270
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  3. XM_012466518.2 → XP_012321941.1  apoptosis-inducing factor 3 isoform X5

    See identical proteins and their annotated locations for XP_012321941.1

    UniProtKB/TrEMBL
    A0A2K5EEF0, A0A2K5EEH4
    Related
    ENSANAP00000031596.1
    Conserved Domains (5) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:334 → 414
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal
    cl21454
    Location:196 → 285
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  4. XM_012466515.2 → XP_012321938.1  apoptosis-inducing factor 3 isoform X4

    UniProtKB/TrEMBL
    A0A2K5EEF0
    Conserved Domains (5) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:334 → 414
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal
    cl21454
    Location:196 → 285
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  5. XM_012466513.3 → XP_012321936.1  apoptosis-inducing factor 3 isoform X1

    See identical proteins and their annotated locations for XP_012321936.1

    UniProtKB/TrEMBL
    A0A2K5EEF0
    Conserved Domains (5) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:334 → 414
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal
    cl21454
    Location:196 → 285
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  6. XM_012466520.3 → XP_012321943.1  apoptosis-inducing factor 3 isoform X7

    Conserved Domains (4) summary
    pfam00070
    Location:154 → 234
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:15 → 313
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:332 → 382
    Reductase_C; Reductase C-terminal
    cl21454
    Location:16 → 105
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  7. XM_012466521.3 → XP_012321944.1  apoptosis-inducing factor 3 isoform X9

    Conserved Domains (3) summary
    pfam00070
    Location:101 → 181
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:13 → 260
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:279 → 329
    Reductase_C; Reductase C-terminal

  8. XM_012466519.2 → XP_012321942.1  apoptosis-inducing factor 3 isoform X6

    UniProtKB/TrEMBL
    A0A2K5EEF0
    Related
    ENSANAP00000031607.1
    Conserved Domains (5) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:334 → 414
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal
    cl21454
    Location:196 → 285
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  9. XM_012466516.2 → XP_012321939.1  apoptosis-inducing factor 3 isoform X5

    See identical proteins and their annotated locations for XP_012321939.1

    UniProtKB/TrEMBL
    A0A2K5EEF0, A0A2K5EEH4
    Conserved Domains (5) summary
    cd03478
    Location:70 → 164
    Rieske_AIFL_N; AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The ...
    pfam00070
    Location:334 → 414
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:195 → 493
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14759
    Location:512 → 562
    Reductase_C; Reductase C-terminal
    cl21454
    Location:196 → 285
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

  10. XM_064371887.1 → XP_064227957.1  apoptosis-inducing factor 3 isoform X8

Nucleotide Protein
Heading Accession and Version

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