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EGLN2 egl-9 family hypoxia inducible factor 2 [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105723436, updated on 15-Apr-2024

Summary

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Gene symbol
EGLN2
Gene description
egl-9 family hypoxia inducible factor 2
See related
Ensembl:ENSANAG00000026190
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988441.1 (13244809..13253636, complement)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018493884.1 (1448538..1457416, complement)

NW_026988441.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 2 subfamily A member 6 Neighboring gene cytochrome P450 family 2 subfamily F member 1 Neighboring gene RAB4B, member RAS oncogene family Neighboring gene MIA SH3 domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ferrous iron binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptidyl-proline 4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prolyl hydroxylase EGLN2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988441.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    13244809..13253636 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021670419.2 → XP_021526094.1  prolyl hydroxylase EGLN2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5D6S1
    Related
    ENSANAP00000016654.1
    Conserved Domains (1) summary
    smart00702
    Location:198 → 374
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues

  2. XM_012461450.3 → XP_012316873.1  prolyl hydroxylase EGLN2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5D6S1
    Conserved Domains (1) summary
    smart00702
    Location:198 → 374
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues

  3. XM_064381292.1 → XP_064237362.1  prolyl hydroxylase EGLN2 isoform X2

  4. XM_064381294.1 → XP_064237364.1  prolyl hydroxylase EGLN2 isoform X4

  5. XM_064381293.1 → XP_064237363.1  prolyl hydroxylase EGLN2 isoform X3

RNA

  1. XR_010344265.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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