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PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105716060, updated on 19-Apr-2024

Summary

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Gene symbol
PPM1B
Gene description
protein phosphatase, Mg2+/Mn2+ dependent 1B
See related
Ensembl:ENSANAG00000025216
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988471.1 (42974348..43044060)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018495252.1 (2204159..2287654, complement)

NW_026988471.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein R-like Neighboring gene all trans-polyprenyl-diphosphate synthase PDSS1-like Neighboring gene small nucleolar RNA U13 Neighboring gene solute carrier family 3 member 1 Neighboring gene prolyl endopeptidase like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988471.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    42974348..43044060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012450599.2 → XP_012306022.1  protein phosphatase 1B isoform X2

    See identical proteins and their annotated locations for XP_012306022.1

    UniProtKB/TrEMBL
    A0A2K5D177
    Conserved Domains (2) summary
    cd00143
    Location:23 → 295
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:289 → 368
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain

  2. XM_012450596.2 → XP_012306019.1  protein phosphatase 1B isoform X1

    See identical proteins and their annotated locations for XP_012306019.1

    UniProtKB/TrEMBL
    A0A2K5D149
    Conserved Domains (2) summary
    cd00143
    Location:23 → 295
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
    pfam07830
    Location:289 → 365
    PP2C_C; Protein serine/threonine phosphatase 2C, C-terminal domain
Nucleotide Protein
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