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ARHGEF10 Rho guanine nucleotide exchange factor 10 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105601351, updated on 13-Mar-2024

Summary

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Gene symbol
ARHGEF10
Gene description
Rho guanine nucleotide exchange factor 10
See related
Ensembl:ENSCATG00000011099
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
32
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012002810.1 (176229..318933, complement)

NW_012002810.1Genomic Context describing neighboring genes Neighboring gene kelch repeat and BTB domain containing 11 Neighboring gene collagen alpha-4(IV) chain-like Neighboring gene uncharacterized LOC105601350 Neighboring gene uncharacterized LOC105601352 Neighboring gene uncharacterized LOC105601353 Neighboring gene CLN8 transmembrane ER and ERGIC protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012002810.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic spindle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of stress fiber assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012002810.1 Reference Caty_1.0

    Range
    176229..318933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012093535.1 → XP_011948925.1  rho guanine nucleotide exchange factor 10 isoform X1

    See identical proteins and their annotated locations for XP_011948925.1

    UniProtKB/TrEMBL
    A0A2K5KPV4, A0A2K5KPV7
    Related
    ENSCATP00000002728.1, ENSCATT00000012990.1
    Conserved Domains (2) summary
    pfam00621
    Location:405 → 583
    RhoGEF; RhoGEF domain
    cl17171
    Location:614 → 707
    PH-like; Pleckstrin homology-like domain

  2. XM_012093536.1 → XP_011948926.1  rho guanine nucleotide exchange factor 10 isoform X1

    See identical proteins and their annotated locations for XP_011948926.1

    UniProtKB/TrEMBL
    A0A2K5KPV4, A0A2K5KPV7
    Conserved Domains (2) summary
    pfam00621
    Location:405 → 583
    RhoGEF; RhoGEF domain
    cl17171
    Location:614 → 707
    PH-like; Pleckstrin homology-like domain

  3. XM_012093537.1 → XP_011948927.1  rho guanine nucleotide exchange factor 10 isoform X2

    UniProtKB/TrEMBL
    A0A2K5KPV4
    Conserved Domains (2) summary
    pfam00621
    Location:287 → 465
    RhoGEF; RhoGEF domain
    cl17171
    Location:496 → 589
    PH-like; Pleckstrin homology-like domain

  4. XM_012093538.1 → XP_011948928.1  rho guanine nucleotide exchange factor 10 isoform X3

    UniProtKB/TrEMBL
    A0A2K5KPV4
    Conserved Domains (2) summary
    pfam00621
    Location:199 → 377
    RhoGEF; RhoGEF domain
    cl17171
    Location:408 → 501
    PH-like; Pleckstrin homology-like domain

  5. XM_012093539.1 → XP_011948929.1  rho guanine nucleotide exchange factor 10 isoform X4

    UniProtKB/TrEMBL
    A0A2K5KPV4
    Conserved Domains (2) summary
    pfam00621
    Location:176 → 354
    RhoGEF; RhoGEF domain
    cl17171
    Location:385 → 478
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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