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TJP3 tight junction protein 3 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105591884, updated on 13-Mar-2024

Summary

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Gene symbol
TJP3
Gene description
tight junction protein 3
See related
Ensembl:ENSCATG00000038428
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001295.1 (3663339..3697342)

NW_012001295.1Genomic Context describing neighboring genes Neighboring gene cactin, spliceosome C complex subunit Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Neighboring gene amyloid beta precursor protein binding family A member 3 Neighboring gene mitochondrial ribosomal protein L54

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001295.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001295.1 Reference Caty_1.0

    Range
    3663339..3697342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012073303.1 → XP_011928693.1  tight junction protein ZO-3

    UniProtKB/TrEMBL
    A0A2K5MZL1
    Related
    ENSCATP00000030514.1, ENSCATT00000054777.1
    Conserved Domains (4) summary
    cd12028
    Location:481 → 551
    SH3_ZO-3; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 3
    smart00072
    Location:593 → 769
    GuKc; Guanylate kinase homologues
    cd00992
    Location:386 → 465
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:624 → 768
    Guanylate_kin; Guanylate kinase
Nucleotide Protein
Heading Accession and Version

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