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MLH3 mutL homolog 3 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105590863, updated on 13-Mar-2024

Summary

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Gene symbol
MLH3
Gene description
mutL homolog 3
See related
Ensembl:ENSCATG00000037886
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See MLH3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001186.1 (1455444..1491400, complement)

NW_012001186.1Genomic Context describing neighboring genes Neighboring gene placental growth factor Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene acylphosphatase 1 Neighboring gene zinc finger C2HC-type containing 1C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001186.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA mismatch repair protein Mlh3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001186.1 Reference Caty_1.0

    Range
    1455444..1491400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012070879.1 → XP_011926269.1  DNA mismatch repair protein Mlh3 isoform X2

    UniProtKB/TrEMBL
    A0A2K5MVM8, A0A2K5MVN3
    Related
    ENSCATP00000029292.1, ENSCATT00000053548.1
    Conserved Domains (3) summary
    smart00853
    Location:1159 → 1338
    MutL_C; MutL C terminal dimerisation domain
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; MutL_Trans_MLH3: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to ...
    pfam02518
    Location:22 → 149
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

  2. XM_012070878.1 → XP_011926268.1  DNA mismatch repair protein Mlh3 isoform X1

    See identical proteins and their annotated locations for XP_011926268.1

    UniProtKB/TrEMBL
    A0A2K5MW41
    Conserved Domains (2) summary
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; MutL_Trans_MLH3: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to ...
    pfam02518
    Location:22 → 149
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase

  3. XM_012070877.1 → XP_011926267.1  DNA mismatch repair protein Mlh3 isoform X1

    See identical proteins and their annotated locations for XP_011926267.1

    UniProtKB/TrEMBL
    A0A2K5MW41
    Conserved Domains (2) summary
    cd03486
    Location:206 → 349
    MutL_Trans_MLH3; MutL_Trans_MLH3: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH3 (MutL homologue 3). MLH3 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to ...
    pfam02518
    Location:22 → 149
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Nucleotide Protein
Heading Accession and Version

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