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MARS1 methionyl-tRNA synthetase 1 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105587251, updated on 13-Mar-2024

Summary

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Gene symbol
MARS1
Gene description
methionyl-tRNA synthetase 1
See related
Ensembl:ENSCATG00000038907
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Also known as
MARS
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012000583.1 (4507158..4534534, complement)

NW_012000583.1Genomic Context describing neighboring genes Neighboring gene dynactin subunit 2 Neighboring gene uncharacterized LOC105587253 Neighboring gene methyl-CpG binding domain protein 6 Neighboring gene DNA damage inducible transcript 3 Neighboring gene Rho GTPase activating protein 9 Neighboring gene GLI family zinc finger 1 Neighboring gene uncharacterized LOC105587260 Neighboring gene inhibin subunit beta E

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012000583.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methionine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in methionyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of aminoacyl-tRNA synthetase multienzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methionine--tRNA ligase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012000583.1 Reference Caty_1.0

    Range
    4507158..4534534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012063299.1 → XP_011918689.1  methionine--tRNA ligase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A2K5N2A6
    Related
    ENSCATP00000031627.1, ENSCATT00000055893.1
    Conserved Domains (7) summary
    cd07957
    Location:642 → 771
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:265 → 633
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    COG0625
    Location:47 → 189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    PRK12268
    Location:264 → 819
    PRK12268; methionyl-tRNA synthetase; Reviewed
    cd00939
    Location:853 → 897
    MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
    cl00388
    Location:27 → 68
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_012063300.1 → XP_011918690.1  methionine--tRNA ligase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A2K5N2T0
    Related
    ENSCATP00000031630.1, ENSCATT00000055896.1
    Conserved Domains (7) summary
    cd07957
    Location:642 → 771
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:265 → 633
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    COG0625
    Location:47 → 189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    PRK12268
    Location:264 → 819
    PRK12268; methionyl-tRNA synthetase; Reviewed
    cd00939
    Location:845 → 889
    MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
    cl00388
    Location:27 → 68
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  3. XM_012063301.1 → XP_011918691.1  methionine--tRNA ligase, cytoplasmic isoform X3

    UniProtKB/TrEMBL
    A0A2K5N2A6
    Conserved Domains (6) summary
    cd07957
    Location:597 → 726
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:220 → 588
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    PRK12268
    Location:219 → 774
    PRK12268; methionyl-tRNA synthetase; Reviewed
    cd00939
    Location:808 → 852
    MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
    cl00388
    Location:27 → 68
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    cl02776
    Location:77 → 134
    GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
Nucleotide Protein
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