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PIWIL2 piwi like RNA-mediated gene silencing 2 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105579232, updated on 13-Mar-2024

Summary

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Gene symbol
PIWIL2
Gene description
piwi like RNA-mediated gene silencing 2
See related
Ensembl:ENSCATG00000039784
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
29
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012005823.1 (13886798..13994470, complement)

NW_012005823.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3 catalytic subunit gamma Neighboring gene transcription factor BTF3 pseudogene Neighboring gene solute carrier family 39 member 14 Neighboring gene RNA polymerase III subunit D Neighboring gene phytanoyl-CoA 2-hydroxylase interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012005823.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables piRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in P granule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
piwi-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012005823.1 Reference Caty_1.0

    Range
    13886798..13994470 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012045812.1 → XP_011901202.1  piwi-like protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:314 → 431
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:439 → 883
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:266 → 313
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:145 → 214
    ArgoN; N-terminal domain of argonaute

  2. XM_012045807.1 → XP_011901197.1  piwi-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011901197.1

    UniProtKB/TrEMBL
    A0A2K5N8G1, A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:387 → 504
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:512 → 956
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:339 → 386
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:218 → 287
    ArgoN; N-terminal domain of argonaute

  3. XM_012045806.1 → XP_011901196.1  piwi-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011901196.1

    UniProtKB/TrEMBL
    A0A2K5N8G1, A0A2K5N8G7
    Related
    ENSCATP00000033625.1, ENSCATT00000057899.1
    Conserved Domains (4) summary
    cd02845
    Location:387 → 504
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:512 → 956
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:339 → 386
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:218 → 287
    ArgoN; N-terminal domain of argonaute

  4. XM_012045809.1 → XP_011901199.1  piwi-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011901199.1

    UniProtKB/TrEMBL
    A0A2K5N8G1, A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:387 → 504
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:512 → 956
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:339 → 386
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:218 → 287
    ArgoN; N-terminal domain of argonaute

  5. XM_012045808.1 → XP_011901198.1  piwi-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011901198.1

    UniProtKB/TrEMBL
    A0A2K5N8G1, A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:387 → 504
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:512 → 956
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:339 → 386
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:218 → 287
    ArgoN; N-terminal domain of argonaute

  6. XM_012045805.1 → XP_011901195.1  piwi-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:404 → 521
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:529 → 973
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:356 → 403
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:235 → 304
    ArgoN; N-terminal domain of argonaute

  7. XM_012045811.1 → XP_011901201.1  piwi-like protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A2K5N8G7
    Conserved Domains (4) summary
    cd02845
    Location:322 → 439
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:447 → 891
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:274 → 321
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:153 → 222
    ArgoN; N-terminal domain of argonaute

  8. XM_012045810.1 → XP_011901200.1  piwi-like protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011901200.1

    UniProtKB/TrEMBL
    A0A2K5N8G1, A0A2K5N8G7
    Related
    ENSCATP00000033630.1, ENSCATT00000057904.1
    Conserved Domains (4) summary
    cd02845
    Location:387 → 504
    PAZ_piwi_like; PAZ domain, Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the ...
    cd04658
    Location:512 → 956
    Piwi_piwi-like_Euk; Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of ...
    pfam08699
    Location:339 → 386
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:218 → 287
    ArgoN; N-terminal domain of argonaute
Nucleotide Protein
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