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ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105575151, updated on 13-Mar-2024

Summary

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Gene symbol
ACAP2
Gene description
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
See related
Ensembl:ENSCATG00000037313
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012004056.1 (2448535..2626877)

NW_012004056.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105575153 Neighboring gene apolipoprotein D Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 Neighboring gene transcription and mRNA export factor ENY2 pseudogene Neighboring gene xyloside xylosyltransferase 1 Neighboring gene uncharacterized LOC105575157

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012004056.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012004056.1 Reference Caty_1.0

    Range
    2448535..2626877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012036745.1 → XP_011892135.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X2

    See identical proteins and their annotated locations for XP_011892135.1

    UniProtKB/TrEMBL
    A0A2K5MSA8, A0A2K5MSG6
    Related
    ENSCATP00000028122.1, ENSCATT00000052373.1
    Conserved Domains (7) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:406 → 521
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:614 → 730
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:273 → 369
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:271 → 365
    PH; PH domain
    pfam12796
    Location:614 → 708
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:642 → 675
    ANK; ANK repeat [structural motif]

  2. XM_012036744.1 → XP_011892134.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011892134.1

    UniProtKB/TrEMBL
    A0A2K5MSG6
    Conserved Domains (7) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:402 → 517
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:645 → 761
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:269 → 365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    pfam00169
    Location:267 → 361
    PH; PH domain
    pfam12796
    Location:645 → 739
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:673 → 706
    ANK; ANK repeat [structural motif]

  3. XM_012036746.1 → XP_011892136.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X3

    See identical proteins and their annotated locations for XP_011892136.1

    UniProtKB/TrEMBL
    A0A2K5MSG6, A0A2K5MSR5
    Related
    ENSCATP00000028130.1, ENSCATT00000052381.1
    Conserved Domains (5) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:402 → 517
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:610 → 726
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:269 → 365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:638 → 671
    ANK; ANK repeat [structural motif]

  4. XM_012036747.1 → XP_011892137.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X4

    See identical proteins and their annotated locations for XP_011892137.1

    UniProtKB/TrEMBL
    A0A2K5MSE0, A0A2K5MSG6
    Related
    ENSCATP00000028131.1, ENSCATT00000052382.1
    Conserved Domains (5) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:406 → 521
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:649 → 765
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:273 → 369
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:677 → 710
    ANK; ANK repeat [structural motif]
Nucleotide Protein
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