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HNRNPU heterogeneous nuclear ribonucleoprotein U [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105574956, updated on 13-Mar-2024

Summary

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Gene symbol
HNRNPU
Gene description
heterogeneous nuclear ribonucleoprotein U
See related
Ensembl:ENSCATG00000035273
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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See HNRNPU in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012003946.1 (16169583..16189959, complement)

NW_012003946.1Genomic Context describing neighboring genes Neighboring gene desumoylating isopeptidase 2 Neighboring gene cytochrome c oxidase protein 20 homolog Neighboring gene uncharacterized LOC105574957 Neighboring gene ATP synthase subunit f, mitochondrial pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012003946.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II C-terminal domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables TFIIH-class transcription factor complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables poly(C) RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables poly(G) binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pre-mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables promoter-specific chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ribonucleoprotein complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables snRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in CRD-mediated mRNA stabilization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in RNA localization to chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of attachment of mitotic spindle microtubules to kinetochore IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of chromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic spindle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CRD-mediated mRNA stability complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catalytic step 2 spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in inactive sex chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitotic spindle microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitotic spindle midzone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoprotein U

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012003946.1 Reference Caty_1.0

    Range
    16169583..16189959 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012036341.1 → XP_011891731.1  heterogeneous nuclear ribonucleoprotein U isoform X2

    UniProtKB/TrEMBL
    A0A2K5ME15
    Conserved Domains (4) summary
    smart00513
    Location:8 → 42
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    pfam13671
    Location:499 → 643
    AAA_33; AAA domain
    cd12884
    Location:288 → 463
    SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
    cl17190
    Location:499 → 636
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. XM_012036342.1 → XP_011891732.1  heterogeneous nuclear ribonucleoprotein U isoform X3

    See identical proteins and their annotated locations for XP_011891732.1

    UniProtKB/TrEMBL
    A0A2K5ME67
    Related
    ENSCATP00000023484.1, ENSCATT00000047702.1
    Conserved Domains (3) summary
    smart00513
    Location:8 → 42
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd12884
    Location:269 → 444
    SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
    pfam13671
    Location:480 → 624
    AAA_33; AAA domain

  3. XM_012036339.1 → XP_011891729.1  heterogeneous nuclear ribonucleoprotein U isoform X1

    See identical proteins and their annotated locations for XP_011891729.1

    UniProtKB/TrEMBL
    A0A2K5ME30, A0A2K5ME67
    Related
    ENSCATP00000023465.1, ENSCATT00000047682.1
    Conserved Domains (3) summary
    smart00513
    Location:8 → 42
    SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
    cd12884
    Location:288 → 463
    SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
    pfam13671
    Location:499 → 643
    AAA_33; AAA domain

RNA

  1. XR_001011050.1 RNA Sequence

  2. XR_001011049.1 RNA Sequence

Nucleotide Protein
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