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CLCN5 chloride voltage-gated channel 5 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105547686, updated on 13-Mar-2024

Summary

Gene symbol
CLCN5
Gene description
chloride voltage-gated channel 5
See related
Ensembl:ENSMLEG00000006896
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012104198.1 (1274712..1434751, complement)

NW_012104198.1Genomic Context describing neighboring genes Neighboring gene cyclin B3 Neighboring gene A-kinase anchoring protein 4 Neighboring gene uncharacterized LOC105547688 Neighboring gene ubiquitin specific peptidase 27 X-linked

Genomic regions, transcripts, and products

Genomic Sequence:
NW_012104198.1 Unplaced Scaffold Reference Mleu.le_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
H(+)/Cl(-) exchange transporter 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012104198.1 Reference Mleu.le_1.0

    Range
    1274712..1434751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011991346.1XP_011846736.1  H(+)/Cl(-) exchange transporter 5 isoform X1

    See identical proteins and their annotated locations for XP_011846736.1

    UniProtKB/TrEMBL
    A0A2K5XEP2
    Related
    ENSMLEP00000001773.1, ENSMLET00000007693.1
    Conserved Domains (2) summary
    cd03684
    Location:142640
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:651801
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  2. XM_011991347.1XP_011846737.1  H(+)/Cl(-) exchange transporter 5 isoform X1

    See identical proteins and their annotated locations for XP_011846737.1

    UniProtKB/TrEMBL
    A0A2K5XEP2
    Conserved Domains (2) summary
    cd03684
    Location:142640
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:651801
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  3. XM_011991350.1XP_011846740.1  H(+)/Cl(-) exchange transporter 5 isoform X3

    See identical proteins and their annotated locations for XP_011846740.1

    UniProtKB/TrEMBL
    A0A2K5XEP9
    Related
    ENSMLEP00000001783.1, ENSMLET00000007723.1
    Conserved Domains (2) summary
    cd03684
    Location:72570
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:595731
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
  4. XM_011991349.1XP_011846739.1  H(+)/Cl(-) exchange transporter 5 isoform X2

    See identical proteins and their annotated locations for XP_011846739.1

    Conserved Domains (2) summary
    cd03684
    Location:92590
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:615751
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...