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NCK2 NCK adaptor protein 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105542961, updated on 13-Mar-2024

Summary

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Gene symbol
NCK2
Gene description
NCK adaptor protein 2
See related
Ensembl:ENSMLEG00000043453
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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See NCK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012102821.1 (2881452..2965711, complement)

NW_012102821.1Genomic Context describing neighboring genes Neighboring gene UDP-glucuronate decarboxylase 1 Neighboring gene ECRG4 augurin precursor

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012102821.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of PERK-mediated unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytoplasmic protein NCK2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012102821.1 Reference Mleu.le_1.0

    Range
    2881452..2965711 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011984687.1 → XP_011840077.1  cytoplasmic protein NCK2 isoform X2

    See identical proteins and their annotated locations for XP_011840077.1

    UniProtKB/TrEMBL
    A0A2K6AFK8
    Related
    ENSMLEP00000038799.1, ENSMLET00000062412.1
    Conserved Domains (1) summary
    cd11899
    Location:4 → 61
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein

  2. XM_011984686.1 → XP_011840076.1  cytoplasmic protein NCK2 isoform X1

    See identical proteins and their annotated locations for XP_011840076.1

    UniProtKB/TrEMBL
    A0A2K6AFG1
    Related
    ENSMLEP00000038801.1, ENSMLET00000062414.1
    Conserved Domains (4) summary
    cd10409
    Location:285 → 382
    SH2_Nck2; Src homology 2 (SH2) domain found in Nck
    cd11899
    Location:4 → 61
    SH3_Nck2_1; First Src Homology 3 domain of Nck2 adaptor protein
    cd11902
    Location:116 → 170
    SH3_Nck2_2; Second Src Homology 3 domain of Nck2 adaptor protein
    cd11903
    Location:200 → 258
    SH3_Nck2_3; Third Src Homology 3 domain of Nck2 adaptor protein
Nucleotide Protein
Heading Accession and Version

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