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HNF1A HNF1 homeobox A [ Mandrillus leucophaeus (drill) ]

Gene ID: 105527943, updated on 13-Mar-2024

Summary

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Gene symbol
HNF1A
Gene description
HNF1 homeobox A
See related
Ensembl:ENSMLEG00000039623
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012107585.1 (6417615..6440870)

NW_012107585.1Genomic Context describing neighboring genes Neighboring gene signal peptide peptidase like 3 Neighboring gene chloride intracellular channel protein 1 pseudogene Neighboring gene chromosome unknown open reading frame, human C12orf43 Neighboring gene 2'-5'-oligoadenylate synthetase like Neighboring gene ret finger protein-like 3 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012107585.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in liver development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pancreas development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hepatocyte nuclear factor 1-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012107585.1 Reference Mleu.le_1.0

    Range
    6417615..6440870
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011964458.1 → XP_011819848.1  hepatocyte nuclear factor 1-alpha isoform X1

    UniProtKB/TrEMBL
    A0A2K5ZT55
    Related
    ENSMLEP00000030976.1, ENSMLET00000054542.1
    Conserved Domains (4) summary
    cd00086
    Location:200 → 273
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam04812
    Location:282 → 540
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
    pfam04813
    Location:573 → 661
    HNF-1A_C; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
    pfam04814
    Location:8 → 167
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus

  2. XM_011964460.1 → XP_011819850.1  hepatocyte nuclear factor 1-alpha isoform X3

    UniProtKB/TrEMBL
    A0A2K5ZT33
    Related
    ENSMLEP00000030979.1, ENSMLET00000054545.1
    Conserved Domains (4) summary
    cd00086
    Location:200 → 273
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam04812
    Location:282 → 540
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
    pfam04813
    Location:542 → 630
    HNF-1A_C; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
    pfam04814
    Location:8 → 167
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus

  3. XM_011964459.1 → XP_011819849.1  hepatocyte nuclear factor 1-alpha isoform X2

    Conserved Domains (4) summary
    cd00086
    Location:200 → 273
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam04812
    Location:282 → 540
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
    pfam04813
    Location:549 → 637
    HNF-1A_C; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
    pfam04814
    Location:8 → 167
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus
Nucleotide Protein
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