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HCK HCK proto-oncogene, Src family tyrosine kinase [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105305509, updated on 11-Apr-2024

Summary

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Gene symbol
HCK
Gene description
HCK proto-oncogene, Src family tyrosine kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011889169.1 (1292353..1329327)

NW_011889169.1Genomic Context describing neighboring genes Neighboring gene XK related 7 Neighboring gene CCM2 like scaffold protein Neighboring gene uncharacterized LOC105305511 Neighboring gene 5S ribosomal RNA Neighboring gene transmembrane 9 superfamily member 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011889169 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011889169.1 Reference Pvam_2.0

    Range
    1292353..1329327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011380150.2 → XP_011378452.1  tyrosine-protein kinase HCK isoform X2

    UniProtKB/TrEMBL
    A0A6P3RJL1
    Conserved Domains (3) summary
    cd10363
    Location:118 → 221
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    cl17036
    Location:60 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:232 → 502
    PKc_like; Protein Kinases, catalytic domain

  2. XM_023523256.1 → XP_023379024.1  tyrosine-protein kinase HCK isoform X1

    UniProtKB/TrEMBL
    A0A6P6BVD4
    Conserved Domains (3) summary
    cd10363
    Location:134 → 237
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    cl17036
    Location:76 → 131
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:248 → 518
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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