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ARHGAP42 Rho GTPase activating protein 42 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105298270, updated on 30-Mar-2024

Summary

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Gene symbol
ARHGAP42
Gene description
Rho GTPase activating protein 42
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011888929.1 (2468185..2710060)

NW_011888929.1Genomic Context describing neighboring genes Neighboring gene contactin 5 Neighboring gene 40S ribosomal protein S4-like Neighboring gene uncharacterized LOC111745204 Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene progesterone receptor Neighboring gene transient receptor potential cation channel subfamily C member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011888929 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 42

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011888929.1 Reference Pvam_2.0

    Range
    2468185..2710060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011369414.2 → XP_011367716.1  rho GTPase-activating protein 42 isoform X1

    See identical proteins and their annotated locations for XP_011367716.1

    UniProtKB/TrEMBL
    A0A6P3QNA0
    Conserved Domains (4) summary
    cd07634
    Location:19 → 225
    BAR_GAP10-like; The Bin/Amphiphysin/Rvs (BAR) domain of Rho GTPase activating protein 10-like
    cd12066
    Location:820 → 874
    SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
    cd04374
    Location:369 → 567
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:267 → 376
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain

  2. XM_023536120.1 → XP_023391888.1  rho GTPase-activating protein 42 isoform X2

    UniProtKB/TrEMBL
    A0A6P6CX46
    Conserved Domains (4) summary
    cd12066
    Location:785 → 839
    SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
    cd04374
    Location:334 → 532
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:232 → 341
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl12013
    Location:19 → 199
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  3. XM_023536121.1 → XP_023391889.1  rho GTPase-activating protein 42 isoform X3

    UniProtKB/TrEMBL
    A0A6P6CWL7
    Conserved Domains (4) summary
    cd12066
    Location:732 → 786
    SH3_GRAF3; Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3
    cd04374
    Location:281 → 479
    RhoGAP_Graf; GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences cytoskeletal ...
    cd01249
    Location:179 → 288
    BAR-PH_GRAF_family; GTPase Regulator Associated with Focal adhesion and related proteins Pleckstrin homology (PH) domain
    cl12013
    Location:41 → 137
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
Heading Accession and Version

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