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LOC105295856 intersectin-1 [ Pteropus vampyrus (large flying fox) ]

Gene ID: 105295856, updated on 30-Mar-2024

Summary

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Gene symbol
LOC105295856
Gene description
intersectin-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus vampyrus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Also known as
ITSN1
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Genomic context

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See LOC105295856 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
32
Annotation release Status Assembly Chr Location
101 current Pvam_2.0 (GCF_000151845.1) Unplaced Scaffold NW_011888895.1 (3183486..3323673, complement)

NW_011888895.1Genomic Context describing neighboring genes Neighboring gene intersectin-1-like Neighboring gene intersectin-1-like Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC111743451 Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene crystallin zeta like 1 Neighboring gene 5S ribosomal RNA Neighboring gene DNA replication fork stabilization factor DONSON Neighboring gene SON DNA and RNA binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011888895 Unplaced Scaffold Reference Pvam_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in clathrin-dependent synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endosomal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in clathrin-coated pit IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
intersectin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus vampyrus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pvam_2.0

Genomic

  1. NW_011888895.1 Reference Pvam_2.0

    Range
    3183486..3323673 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023533878.1 → XP_023389646.1  intersectin-1 isoform X6

    UniProtKB/TrEMBL
    A0A6P6CQ16
    Conserved Domains (8) summary
    smart00027
    Location:214 → 309
    EH; Eps15 homology domain
    cd11839
    Location:1003 → 1060
    SH3_Intersectin_4; Fourth Src homology 3 domain (or SH3D) of Intersectin
    cd11987
    Location:744 → 798
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11995
    Location:1083 → 1136
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:798 → 912
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:912 → 963
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:439 → 686
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:131 → 202
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  2. XM_023533874.1 → XP_023389642.1  intersectin-1 isoform X2

    UniProtKB/TrEMBL
    A0A6P6CQC9
    Conserved Domains (8) summary
    smart00027
    Location:214 → 309
    EH; Eps15 homology domain
    cd11987
    Location:744 → 798
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:1002 → 1053
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:1154 → 1207
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:798 → 912
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:1070 → 1134
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:439 → 686
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:131 → 202
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  3. XM_023533877.1 → XP_023389645.1  intersectin-1 isoform X5

    UniProtKB/TrEMBL
    A0A6P6CRW0
    Conserved Domains (8) summary
    smart00027
    Location:214 → 309
    EH; Eps15 homology domain
    cd11839
    Location:1042 → 1099
    SH3_Intersectin_4; Fourth Src homology 3 domain (or SH3D) of Intersectin
    cd11987
    Location:744 → 798
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11995
    Location:1122 → 1175
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:798 → 951
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:951 → 1002
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:439 → 686
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:131 → 202
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  4. XM_023533872.1 → XP_023389640.1  intersectin-1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6CRV5
    Conserved Domains (8) summary
    smart00027
    Location:214 → 309
    EH; Eps15 homology domain
    cd11987
    Location:744 → 798
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:1041 → 1092
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:1193 → 1246
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:798 → 951
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:1109 → 1173
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:439 → 686
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:131 → 202
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  5. XM_023533876.1 → XP_023389644.1  intersectin-1 isoform X4

    UniProtKB/TrEMBL
    A0A6P6CQI3
    Conserved Domains (9) summary
    smart00027
    Location:154 → 249
    EH; Eps15 homology domain
    cd11987
    Location:684 → 738
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:981 → 1032
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:1133 → 1186
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:738 → 891
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:1049 → 1113
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:379 → 626
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:71 → 142
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    cl27812
    Location:3 → 48
    EF-hand_4; Cytoskeletal-regulatory complex EF hand

  6. XM_023533873.1 → XP_023389641.1  intersectin-1 isoform X1

    UniProtKB/TrEMBL
    A0A6P6CRV5
    Conserved Domains (8) summary
    smart00027
    Location:214 → 309
    EH; Eps15 homology domain
    cd11987
    Location:744 → 798
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:1041 → 1092
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:1193 → 1246
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:798 → 951
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:1109 → 1173
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:439 → 686
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:131 → 202
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]

  7. XM_023533875.1 → XP_023389643.1  intersectin-1 isoform X3

    UniProtKB/TrEMBL
    A0A6P6CQR9
    Conserved Domains (9) summary
    smart00027
    Location:166 → 261
    EH; Eps15 homology domain
    cd11987
    Location:696 → 750
    SH3_Intersectin1_1; First Src homology 3 domain (or SH3A) of Intersectin-1
    cd11991
    Location:993 → 1044
    SH3_Intersectin1_3; Third Src homology 3 domain (or SH3C) of Intersectin-1
    cd11995
    Location:1145 → 1198
    SH3_Intersectin1_5; Fifth Src homology 3 domain (or SH3E) of Intersectin-1
    pfam16617
    Location:750 → 903
    INTAP; Intersectin and clathrin adaptor AP2 binding region
    cl17036
    Location:1061 → 1125
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:391 → 638
    SMC_N; RecF/RecN/SMC N terminal domain
    cl27427
    Location:83 → 154
    AccB; Biotin carboxyl carrier protein [Coenzyme transport and metabolism, Lipid transport and metabolism]
    cl27812
    Location:15 → 60
    EF-hand_4; Cytoskeletal-regulatory complex EF hand
Nucleotide Protein
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