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zgc:123258 PA_hSPPL_like and Peptidase_A22B domain-containing protein [ Esox lucius (northern pike) ]

Gene ID: 105022651, updated on 13-Mar-2024

Summary

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Gene symbol
zgc:123258
Gene description
PA_hSPPL_like and Peptidase_A22B domain-containing protein
See related
EnsemblRapid:ENSELUG00000004367
Gene type
protein coding
RefSeq status
MODEL
Organism
Esox lucius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes; Esocidae; Esox
Also known as
sppl2a
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
104 current fEsoLuc1.pri (GCF_011004845.1) 2 NC_047570.1 (27265474..27282870, complement)
103 previous assembly Eluc_v4 (GCF_004634155.1) Linkage Group LG02 NC_025969.4 (12689185..12706870)

Chromosome 2 - NC_047570.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily M member 7-like Neighboring gene transient receptor potential cation channel subfamily M member 7 Neighboring gene uncharacterized LOC105022652 Neighboring gene uncharacterized LOC109616413

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 2A
Names
signal peptide peptidase like 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Esox lucius Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEsoLuc1.pri Primary Assembly

Genomic

  1. NC_047570.1 Reference fEsoLuc1.pri Primary Assembly

    Range
    27265474..27282870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010891270.4 → XP_010889572.2  signal peptide peptidase-like 2A isoform X3

    UniProtKB/TrEMBL
    A0A3P8ZGR1
    Related
    ENSELUP00000054831.2, ENSELUT00000053264.2
    Conserved Domains (2) summary
    cl28883
    Location:37 → 156
    PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
    cl01342
    Location:219 → 495
    Peptidase_A22B; Signal peptide peptidase

  2. XM_010891269.5 → XP_010889571.2  signal peptide peptidase-like 2A isoform X2

    UniProtKB/TrEMBL
    A0A3P8ZGR1
    Related
    ENSELUP00000003057.2, ENSELUT00000014667.3
    Conserved Domains (2) summary
    cl28883
    Location:37 → 156
    PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
    cl01342
    Location:219 → 510
    Peptidase_A22B; Signal peptide peptidase

  3. XM_010891268.5 → XP_010889570.2  signal peptide peptidase-like 2A isoform X1

    UniProtKB/TrEMBL
    A0A3P8ZGR1
    Related
    ENSELUP00000027946.2, ENSELUT00000014643.3
    Conserved Domains (2) summary
    cl28883
    Location:37 → 156
    PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
    cl01342
    Location:219 → 510
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
Heading Accession and Version

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