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dgkaa diacylglycerol kinase, alpha a [ Esox lucius (northern pike) ]

Gene ID: 105022307, updated on 13-Mar-2024

Summary

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Gene symbol
dgkaa
Gene description
diacylglycerol kinase, alpha a
See related
EnsemblRapid:ENSELUG00000003323
Gene type
protein coding
RefSeq status
MODEL
Organism
Esox lucius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes; Esocidae; Esox
Also known as
dgka
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: 12
Exon count:
27
Annotation release Status Assembly Chr Location
104 current fEsoLuc1.pri (GCF_011004845.1) 12 NC_047580.1 (25707698..25732515, complement)
103 previous assembly Eluc_v4 (GCF_004634155.1) Linkage Group LG12 NC_025979.4 (11573023..11597781)

Chromosome 12 - NC_047580.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 4, group A, member 1 Neighboring gene trafficking regulator and scaffold protein tamalin Neighboring gene uncharacterized LOC114840507 Neighboring gene uncharacterized LOC105022305 Neighboring gene ring finger protein 41 Neighboring gene solute carrier family 39 member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase, alpha a
Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Esox lucius Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fEsoLuc1.pri Primary Assembly

Genomic

  1. NC_047580.1 Reference fEsoLuc1.pri Primary Assembly

    Range
    25707698..25732515 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010890569.3 → XP_010888871.1  diacylglycerol kinase, alpha a

    See identical proteins and their annotated locations for XP_010888871.1

    UniProtKB/TrEMBL
    A0A3P8XFP1, A0A6Q2XXF5
    Conserved Domains (6) summary
    smart00046
    Location:379 → 500
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:209 → 258
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:118 → 187
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl00040
    Location:274 → 326
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam14513
    Location:12 → 113
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cl02440
    Location:521 → 698
    DAGK_acc; Diacylglycerol kinase accessory domain

  2. XM_020051337.3 → XP_019906896.1  diacylglycerol kinase, alpha a

    UniProtKB/TrEMBL
    A0A3P8XFP1, A0A6Q2XXF5
    Related
    ENSELUP00000072779.2, ENSELUT00000051016.2
    Conserved Domains (6) summary
    smart00046
    Location:379 → 500
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:209 → 258
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:118 → 187
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl00040
    Location:274 → 326
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam14513
    Location:12 → 113
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cl02440
    Location:521 → 698
    DAGK_acc; Diacylglycerol kinase accessory domain

  3. XM_010890568.4 → XP_010888870.1  diacylglycerol kinase, alpha a

    See identical proteins and their annotated locations for XP_010888870.1

    UniProtKB/TrEMBL
    A0A3P8XFP1, A0A6Q2XXF5
    Related
    ENSELUP00000001912.1, ENSELUT00000016599.3
    Conserved Domains (6) summary
    smart00046
    Location:379 → 500
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:209 → 258
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:118 → 187
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl00040
    Location:274 → 326
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam14513
    Location:12 → 113
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cl02440
    Location:521 → 698
    DAGK_acc; Diacylglycerol kinase accessory domain

  4. XM_010890570.5 → XP_010888872.1  diacylglycerol kinase, alpha a

    See identical proteins and their annotated locations for XP_010888872.1

    UniProtKB/TrEMBL
    A0A3P8XFP1, A0A6Q2XXF5
    Conserved Domains (6) summary
    smart00046
    Location:379 → 500
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:209 → 258
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:118 → 187
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl00040
    Location:274 → 326
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam14513
    Location:12 → 113
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cl02440
    Location:521 → 698
    DAGK_acc; Diacylglycerol kinase accessory domain

  5. XM_010890571.3 → XP_010888873.1  diacylglycerol kinase, alpha a

    See identical proteins and their annotated locations for XP_010888873.1

    UniProtKB/TrEMBL
    A0A3P8XFP1, A0A6Q2XXF5
    Conserved Domains (6) summary
    smart00046
    Location:379 → 500
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:209 → 258
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:118 → 187
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cl00040
    Location:274 → 326
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam14513
    Location:12 → 113
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cl02440
    Location:521 → 698
    DAGK_acc; Diacylglycerol kinase accessory domain
Nucleotide Protein
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