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Chrna2 cholinergic receptor nicotinic alpha 2 subunit [ Fukomys damarensis (Damara mole-rat) ]

Gene ID: 104861861, updated on 12-Mar-2024

Summary

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Gene symbol
Chrna2
Gene description
cholinergic receptor nicotinic alpha 2 subunit
Locus tag
H920_00483
See related
Ensembl:ENSFDAG00000018285
Gene type
protein coding
RefSeq status
MODEL
Organism
Fukomys damarensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900930.1 (47040419..47054270, complement)
101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011043248.1 (3401110..3414915)

NW_022900930.1Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 35 Neighboring gene protein tyrosine kinase 2 beta Neighboring gene epoxide hydrolase 2 Neighboring gene uncharacterized LOC104861841

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neuronal acetylcholine receptor subunit alpha-2
Names
Neuronal acetylcholine receptor subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DMR_v1.0_HiC Primary Assembly

Genomic

  1. NW_022900930.1 Reference DMR_v1.0_HiC Primary Assembly

    Range
    47040419..47054270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033765497.1 → XP_033621388.1  neuronal acetylcholine receptor subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A091E5T0
    Conserved Domains (2) summary
    TIGR00860
    Location:35 → 504
    LIC; Cation transporter family protein
    cd19015
    Location:36 → 242
    LGIC_ECD_nAChR_A2; extracellular domain of nicotinic acetylcholine receptor subunit alpha 2 (CHRNA2)

  2. XM_010623487.2 → XP_010621789.1  neuronal acetylcholine receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_010621789.1

    UniProtKB/TrEMBL
    A0A091E5T0
    Related
    ENSFDAP00000010551.1
    Conserved Domains (2) summary
    TIGR00860
    Location:35 → 504
    LIC; Cation transporter family protein
    cd19015
    Location:36 → 242
    LGIC_ECD_nAChR_A2; extracellular domain of nicotinic acetylcholine receptor subunit alpha 2 (CHRNA2)

  3. XM_010623496.2 → XP_010621798.1  neuronal acetylcholine receptor subunit alpha-2 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:13 → 482
    LIC; Cation transporter family protein
    pfam02931
    Location:14 → 220
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:227 → 480
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  4. XM_033765498.1 → XP_033621389.1  neuronal acetylcholine receptor subunit alpha-2 isoform X4

    Conserved Domains (2) summary
    cl28912
    Location:1 → 127
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:134 → 387
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  5. XM_033765502.1 → XP_033621393.1  neuronal acetylcholine receptor subunit alpha-2 isoform X5

    Conserved Domains (2) summary
    cl28912
    Location:1 → 106
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:113 → 366
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  6. XM_033765499.1 → XP_033621390.1  neuronal acetylcholine receptor subunit alpha-2 isoform X4

    Conserved Domains (2) summary
    cl28912
    Location:1 → 127
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:134 → 387
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  7. XM_033765503.1 → XP_033621394.1  neuronal acetylcholine receptor subunit alpha-2 isoform X5

    Conserved Domains (2) summary
    cl28912
    Location:1 → 106
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:113 → 366
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  8. XM_033765501.1 → XP_033621392.1  neuronal acetylcholine receptor subunit alpha-2 isoform X4

    Conserved Domains (2) summary
    cl28912
    Location:1 → 127
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:134 → 387
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  9. XM_033765500.1 → XP_033621391.1  neuronal acetylcholine receptor subunit alpha-2 isoform X4

    Conserved Domains (2) summary
    cl28912
    Location:1 → 127
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:134 → 387
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  10. XM_010623502.1 → XP_010621804.1  neuronal acetylcholine receptor subunit alpha-2 isoform X3

    Conserved Domains (2) summary
    pfam02931
    Location:36 → 242
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:249 → 470
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RNA

  1. XR_780144.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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