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Tlr8 toll like receptor 8 [ Fukomys damarensis (Damara mole-rat) ]

Gene ID: 104855182, updated on 12-Mar-2024

Summary

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Gene symbol
Tlr8
Gene description
toll like receptor 8
Locus tag
H920_19325
See related
Ensembl:ENSFDAG00000000174
Gene type
protein coding
RefSeq status
MODEL
Organism
Fukomys damarensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
2
Annotation release Status Assembly Chr Location
102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900951.1 (9461069..9471265)
101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011047730.1 (1046691..1056780, complement)

NW_022900951.1Genomic Context describing neighboring genes Neighboring gene toll like receptor 7 Neighboring gene non-POU domain-containing octamer-binding protein Neighboring gene uncharacterized LOC104855180 Neighboring gene thymosin beta 4 X-linked

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pattern recognition receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interleukin-6 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DMR_v1.0_HiC Primary Assembly

Genomic

  1. NW_022900951.1 Reference DMR_v1.0_HiC Primary Assembly

    Range
    9461069..9471265
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010613969.3 → XP_010612271.1  toll-like receptor 8

    See identical proteins and their annotated locations for XP_010612271.1

    UniProtKB/TrEMBL
    A0A091CPX2
    Related
    ENSFDAP00000013517.1
    Conserved Domains (5) summary
    smart00082
    Location:766 → 806
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:874 → 1010
    TIR; Toll - interleukin 1 - resistance
    cd00116
    Location:517 → 743
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:504 → 525
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:633 → 693
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version

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