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ACAN aggrecan [ Haliaeetus leucocephalus (bald eagle) ]

Gene ID: 104834556, updated on 12-Mar-2024

Summary

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Gene symbol
ACAN
Gene description
aggrecan
Gene type
protein coding
RefSeq status
MODEL
Organism
Haliaeetus leucocephalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Accipitriformes; Accipitridae; Accipitrinae; Haliaeetus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Haliaeetus_leucocephalus-4.0 (GCF_000737465.1) Unplaced Scaffold NW_010972775.1 (15240604..15268126, complement)

NW_010972775.1Genomic Context describing neighboring genes Neighboring gene milk fat globule EGF and factor V/VIII domain containing Neighboring gene hyaluronan and proteoglycan link protein 3 Neighboring gene apoptosis enhancing nuclease Neighboring gene DET1 partner of COP1 E3 ubiquitin ligase Neighboring gene mitochondrial ribosomal protein S11

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010972775.1 Unplaced Scaffold Reference Haliaeetus_leucocephalus-4.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aggrecan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haliaeetus leucocephalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Haliaeetus_leucocephalus-4.0

Genomic

  1. NW_010972775.1 Reference Haliaeetus_leucocephalus-4.0

    Range
    15240604..15268126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010571971.1 → XP_010570273.1  aggrecan core protein

    Conserved Domains (9) summary
    cd00033
    Location:1946 → 2002
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03588
    Location:1819 → 1942
    CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
    smart00410
    Location:36 → 146
    IG_like; Immunoglobulin like
    cd00054
    Location:1777 → 1813
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:149 → 243
    Link_domain_CSPGs_modules_1_3; Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: ...
    cd03520
    Location:250 → 345
    Link_domain_CSPGs_modules_2_4; Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The ...
    pfam05109
    Location:994 → 1624
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam15710
    Location:758 → 1080
    DUF4671; Domain of unknown function (DUF4671)
    cl11960
    Location:43 → 150
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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