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NTRK2 neurotrophic receptor tyrosine kinase 2 [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104673903, updated on 11-Apr-2024

Summary

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Gene symbol
NTRK2
Gene description
neurotrophic receptor tyrosine kinase 2
See related
Ensembl:ENSRROG00000039992
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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See NTRK2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
23
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 16 NC_044564.1 (33501457..33868208)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010821513.1 (923756..1294443, complement)

Chromosome 16 - NC_044564.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene solute carrier family 28 member 3 Neighboring gene ATP/GTP binding carboxypeptidase 1 Neighboring gene prohibitin pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables brain-derived neurotrophic factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables brain-derived neurotrophic factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to brain-derived neurotrophic factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in trans-synaptic signaling by neuropeptide, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
BDNF/NT-3 growth factors receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044564.1 Reference ASM756505v1 Primary Assembly

    Range
    33501457..33868208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010378081.2 → XP_010376383.1  BDNF/NT-3 growth factors receptor isoform X3

    See identical proteins and their annotated locations for XP_010376383.1

    Conserved Domains (6) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96 → 116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:31 → 60
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain

  2. XM_030919805.1 → XP_030775665.1  BDNF/NT-3 growth factors receptor isoform X2

    UniProtKB/TrEMBL
    A0A2K6QVF3
    Conserved Domains (6) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96 → 116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:31 → 60
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain

  3. XM_010378082.2 → XP_010376384.1  BDNF/NT-3 growth factors receptor isoform X4

    See identical proteins and their annotated locations for XP_010376384.1

    UniProtKB/TrEMBL
    A0A2K6QVB9
    Related
    ENSRROP00000032752.1
    Conserved Domains (6) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96 → 116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:31 → 60
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain

  4. XM_030919806.1 → XP_030775666.1  BDNF/NT-3 growth factors receptor isoform X4

    UniProtKB/TrEMBL
    A0A2K6QVB9
    Conserved Domains (6) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96 → 116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:31 → 60
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain

  5. XM_030919807.1 → XP_030775667.1  BDNF/NT-3 growth factors receptor isoform X4

    UniProtKB/TrEMBL
    A0A2K6QVB9
    Conserved Domains (6) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    sd00031
    Location:96 → 116
    LRR_1; leucine-rich repeat [structural motif]
    pfam01462
    Location:31 → 60
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain

  6. XM_010378077.2 → XP_010376379.1  BDNF/NT-3 growth factors receptor isoform X1

    See identical proteins and their annotated locations for XP_010376379.1

    UniProtKB/TrEMBL
    A0A2K6QVF4
    Related
    ENSRROP00000032748.1
    Conserved Domains (5) summary
    cd05855
    Location:301 → 379
    Ig_TrkB_d5; Fifth domain (immunoglobulin-like) of Trk receptor TrkB
    cd05093
    Location:548 → 835
    PTKc_TrkB; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase B
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    pfam16920
    Location:152 → 195
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl11960
    Location:205 → 283
    Ig; Immunoglobulin domain
Nucleotide Protein
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