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LRP2 LDL receptor related protein 2 [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104655037, updated on 12-Mar-2024

Summary

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Gene symbol
LRP2
Gene description
LDL receptor related protein 2
See related
Ensembl:ENSRROG00000035813
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
80
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 14 NC_044562.1 (78865835..79092916)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010829610.1 (1762354..1981980, complement)

Chromosome 14 - NC_044562.1Genomic Context describing neighboring genes Neighboring gene FAST kinase domains 1 Neighboring gene kelch like family member 41 Neighboring gene Bardet-Biedl syndrome 5 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like Neighboring gene dehydrogenase/reductase 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044562.1 Reference ASM756505v1 Primary Assembly

    Range
    78865835..79092916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030916829.1 → XP_030772689.1  low-density lipoprotein receptor-related protein 2

    UniProtKB/TrEMBL
    A0A2K6Q5I5
    Conserved Domains (9) summary
    smart00192
    Location:3639 → 3671
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:1506 → 1548
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1395 → 1434
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:2097 → 2290
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:3764 → 3798
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00058
    Location:4202 → 4242
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam12662
    Location:3137 → 3160
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:2351 → 2387
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:3152 → 3195
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Nucleotide Protein
Heading Accession and Version

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