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ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor 6 [ Tinamus guttatus (white-throated tinamou) ]

Gene ID: 104579005, updated on 12-Mar-2024

Summary

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Gene symbol
ARHGEF6
Gene description
Rac/Cdc42 guanine nucleotide exchange factor 6
Locus tag
N309_10825
Gene type
protein coding
RefSeq status
MODEL
Organism
Tinamus guttatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Tinamiformes; Tinamidae; Tinamus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current ASM70537v2 (GCF_000705375.1) Unplaced Scaffold NW_010589955.1 (80473..113497, complement)

NW_010589955.1Genomic Context describing neighboring genes Neighboring gene MCTS1 re-initiation and release factor Neighboring gene CD40 ligand Neighboring gene transmembrane 9 superfamily member 2-like Neighboring gene RNA binding motif protein X-linked

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010589955.1 Unplaced Scaffold Reference ASM70537v2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 6
Names
Rho guanine nucleotide exchange factor 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tinamus guttatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM70537v2

Genomic

  1. NW_010589955.1 Reference ASM70537v2

    Range
    80473..113497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010226590.1 → XP_010224892.1  rho guanine nucleotide exchange factor 6 isoform X1

    UniProtKB/TrEMBL
    A0A099ZT54
    Conserved Domains (8) summary
    cd12060
    Location:163 → 220
    SH3_alphaPIX; Src Homology 3 domain of alpha-Pak Interactive eXchange factor
    smart00033
    Location:8 → 103
    CH; Calponin homology domain
    cd01225
    Location:451 → 549
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam00169
    Location:451 → 549
    PH; PH domain
    pfam00621
    Location:246 → 421
    RhoGEF; RhoGEF domain
    pfam16523
    Location:678 → 764
    betaPIX_CC; betaPIX coiled coil
    pfam16614
    Location:568 → 675
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:114 → 161
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

  2. XM_010226591.1 → XP_010224893.1  rho guanine nucleotide exchange factor 6 isoform X2

    Conserved Domains (6) summary
    cd12060
    Location:8 → 65
    SH3_alphaPIX; Src Homology 3 domain of alpha-Pak Interactive eXchange factor
    cd01225
    Location:296 → 394
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam00169
    Location:296 → 394
    PH; PH domain
    pfam00621
    Location:91 → 266
    RhoGEF; RhoGEF domain
    pfam16523
    Location:523 → 609
    betaPIX_CC; betaPIX coiled coil
    pfam16614
    Location:413 → 520
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
Nucleotide Protein
Heading Accession and Version

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