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MITF melanocyte inducing transcription factor [ Mesitornis unicolor (brown roatelo) ]

Gene ID: 104544297, updated on 12-Mar-2024

Summary

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Gene symbol
MITF
Gene description
melanocyte inducing transcription factor
Locus tag
N332_13574
Gene type
protein coding
RefSeq status
MODEL
Organism
Mesitornis unicolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current ASM69576v1 (GCF_000695765.1) Unplaced Scaffold NW_010198379.1 (193984..242418, complement)

NW_010198379.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104544299 Neighboring gene pentafunctional AROM polypeptide-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010198379.1 Unplaced Scaffold Reference ASM69576v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microphthalmia-associated transcription factor
Names
melanogenesis associated transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mesitornis unicolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69576v1

Genomic

  1. NW_010198379.1 Reference ASM69576v1

    Range
    193984..242418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010189129.1 → XP_010187431.1  microphthalmia-associated transcription factor isoform X5

    Conserved Domains (4) summary
    cd00083
    Location:257 → 317
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:345 → 470
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 142
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:313 → 348
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  2. XM_010189126.1 → XP_010187428.1  microphthalmia-associated transcription factor isoform X2

    See identical proteins and their annotated locations for XP_010187428.1

    UniProtKB/TrEMBL
    A0A091SFB2
    Conserved Domains (4) summary
    cd00083
    Location:251 → 311
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:339 → 464
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 142
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:307 → 342
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  3. XM_010189128.1 → XP_010187430.1  microphthalmia-associated transcription factor isoform X4

    Conserved Domains (4) summary
    cd00083
    Location:168 → 228
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:256 → 381
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 92
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:224 → 259
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  4. XM_010189125.1 → XP_010187427.1  microphthalmia-associated transcription factor isoform X1

    Conserved Domains (4) summary
    cd00083
    Location:289 → 349
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:377 → 502
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:42 → 180
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:345 → 380
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  5. XM_010189127.1 → XP_010187429.1  microphthalmia-associated transcription factor isoform X3

    Conserved Domains (4) summary
    cd00083
    Location:196 → 256
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:284 → 409
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 87
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:252 → 287
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version

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