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IMPDH2 inosine monophosphate dehydrogenase 2 [ Mesitornis unicolor (brown roatelo) ]

Gene ID: 104533261, updated on 12-Mar-2024

Summary

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Gene symbol
IMPDH2
Gene description
inosine monophosphate dehydrogenase 2
Locus tag
N332_08839
Gene type
protein coding
RefSeq status
MODEL
Organism
Mesitornis unicolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current ASM69576v1 (GCF_000695765.1) Unplaced Scaffold NW_010194962.1 (6..9679, complement)

NW_010194962.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010194962.1 Unplaced Scaffold Reference ASM69576v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IMP dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in GTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inosine-5'-monophosphate dehydrogenase 2
Names
Inosine-5'-monophosphate dehydrogenase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mesitornis unicolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69576v1

Genomic

  1. NW_010194962.1 Reference ASM69576v1

    Range
    6..9679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010187969.1 → XP_010186271.1  inosine-5'-monophosphate dehydrogenase 2

    Conserved Domains (4) summary
    COG0517
    Location:21 → 144
    CBS; CBS domain [Signal transduction mechanisms]
    cd00381
    Location:158 → 380
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
    cd04602
    Location:32 → 147
    CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
    pfam00478
    Location:164 → 380
    IMPDH; IMP dehydrogenase / GMP reductase domain
Nucleotide Protein
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