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LRRK1 leucine rich repeat kinase 1 [ Tyto alba (common barn owl) ]

Gene ID: 104359775, updated on 12-Mar-2024

Summary

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Gene symbol
LRRK1
Gene description
leucine rich repeat kinase 1
Locus tag
N341_02933
Gene type
protein coding
RefSeq status
MODEL
Organism
Tyto alba
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
37
Annotation release Status Assembly Chr Location
102 current T.alba_DEE_v4.0 (GCF_018691265.1) Unplaced Scaffold NW_024881317.1 (3854714..3937050, complement)
100 previous assembly ASM68720v1 (GCF_000687205.1) Unplaced Scaffold NW_009994278.1 (3071..80310)

NW_024881317.1Genomic Context describing neighboring genes Neighboring gene selenoprotein S Neighboring gene chondroitin sulfate synthase 1 Neighboring gene aldehyde dehydrogenase 1 family member A3 Neighboring gene ankyrin repeat and SOCS box containing 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat serine/threonine-protein kinase 1
Names
Leucine-rich repeat serine/threonine-protein kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tyto alba Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T.alba_DEE_v4.0

Genomic

  1. NW_024881317.1 Reference T.alba_DEE_v4.0

    Range
    3854714..3937050 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042804189.1 → XP_042660123.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A093H3S0
    Conserved Domains (5) summary
    COG4886
    Location:247 → 577
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1216 → 1491
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:271 → 293
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:137 → 174
    ANK; ANK repeat [structural motif]
    cl38936
    Location:607 → 789
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_042804188.1 → XP_042660122.1  leucine-rich repeat serine/threonine-protein kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A093H3S0
    Conserved Domains (6) summary
    PLN00113
    Location:433 → 598
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:247 → 506
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1238 → 1513
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:271 → 293
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:137 → 174
    ANK; ANK repeat [structural motif]
    cl38936
    Location:629 → 811
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_032994299.2 → XP_032850190.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A093H3S0
    Conserved Domains (6) summary
    PLN00113
    Location:407 → 572
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:221 → 480
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1212 → 1487
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:245 → 267
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:111 → 148
    ANK; ANK repeat [structural motif]
    cl38936
    Location:603 → 785
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_032994298.2 → XP_032850189.2  leucine-rich repeat serine/threonine-protein kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A093H3S0
    Conserved Domains (6) summary
    PLN00113
    Location:407 → 572
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    COG4886
    Location:221 → 480
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    cd14067
    Location:1212 → 1487
    STKc_LRRK1; Catalytic domain of the Serine/Threonine Kinase, Leucine-Rich Repeat Kinase 1
    sd00033
    Location:245 → 267
    LRR_RI; leucine-rich repeat [structural motif]
    sd00045
    Location:111 → 148
    ANK; ANK repeat [structural motif]
    cl38936
    Location:603 → 785
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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