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TRAF1 TNF receptor associated factor 1 [ Tyto alba (common barn owl) ]

Gene ID: 104359133, updated on 12-Mar-2024

Summary

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Gene symbol
TRAF1
Gene description
TNF receptor associated factor 1
Locus tag
N341_05290
Gene type
protein coding
RefSeq status
MODEL
Organism
Tyto alba
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current T.alba_DEE_v4.0 (GCF_018691265.1) Unplaced Scaffold NW_024881273.1 (2805111..2822833)
100 previous assembly ASM68720v1 (GCF_000687205.1) Unplaced Scaffold NW_009991767.1 (3141..17258)

NW_024881273.1Genomic Context describing neighboring genes Neighboring gene centriolin Neighboring gene complement C5 Neighboring gene uncharacterized LOC122152745 Neighboring gene PHD finger protein 19 Neighboring gene cutA divalent cation tolerance homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 1
Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tyto alba Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T.alba_DEE_v4.0

Genomic

  1. NW_024881273.1 Reference T.alba_DEE_v4.0

    Range
    2805111..2822833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042786468.1 → XP_042642402.1  TNF receptor-associated factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A093EW47
    Conserved Domains (5) summary
    COG5152
    Location:2 → 95
    COG5152; Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only]
    cd03779
    Location:421 → 567
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:338 → 395
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:51 → 93
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:145 → 199
    zf-TRAF; TRAF-type zinc finger

  2. XM_042786472.1 → XP_042642406.1  TNF receptor-associated factor 1 isoform X4

    Conserved Domains (3) summary
    COG5152
    Location:2 → 95
    COG5152; Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers [General function prediction only]
    cl02446
    Location:275 → 421
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    cl17238
    Location:51 → 93
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  3. XM_042786469.1 → XP_042642403.1  TNF receptor-associated factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A093EW47
    Conserved Domains (4) summary
    cd03779
    Location:420 → 566
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam16673
    Location:337 → 394
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:50 → 92
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:144 → 198
    zf-TRAF; TRAF-type zinc finger

  4. XM_042786470.1 → XP_042642404.1  TNF receptor-associated factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A093EW47
    Conserved Domains (3) summary
    cd03779
    Location:409 → 555
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    cl17238
    Location:39 → 81
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:133 → 187
    zf-TRAF; TRAF-type zinc finger

  5. XM_042786471.1 → XP_042642405.1  TNF receptor-associated factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A093EW47
    Conserved Domains (3) summary
    cd03779
    Location:409 → 555
    MATH_TRAF1; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF1 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    cl17238
    Location:39 → 81
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:133 → 187
    zf-TRAF; TRAF-type zinc finger
Nucleotide Protein
Heading Accession and Version

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