U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EGFR epidermal growth factor receptor [ Leptosomus discolor (cuckoo roller) ]

Gene ID: 104345569, updated on 11-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
EGFR
Gene description
epidermal growth factor receptor
Locus tag
N330_03652
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptosomus discolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae; Leptosomus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current ASM69178v1 (GCF_000691785.1) Unplaced Scaffold NW_009861063.1 (33772..79585, complement)

NW_009861063.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_009861063.1 Unplaced Scaffold Reference ASM69178v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epidermal growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epidermal growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
epidermal growth factor receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Leptosomus discolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69178v1

Genomic

  1. NW_009861063.1 Reference ASM69178v1

    Range
    33772..79585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009950055.1 → XP_009948357.1  epidermal growth factor receptor

    UniProtKB/TrEMBL
    A0A091PSE3
    Conserved Domains (8) summary
    smart00219
    Location:690 → 945
    TyrKc; Tyrosine kinase, catalytic domain
    cd12093
    Location:612 → 654
    TM_ErbB1; Transmembrane domain of Epidermal Growth Factor Receptor or ErbB1, a Protein Tyrosine Kinase
    smart00261
    Location:529 → 576
    FU; Furin-like repeats
    cd00064
    Location:206 → 249
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    cd05108
    Location:681 → 993
    PTKc_EGFR; Catalytic domain of the Protein Tyrosine Kinase, Epidermal Growth Factor Receptor
    pfam00757
    Location:162 → 310
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:31 → 143
    Recep_L_domain; Receptor L domain
    pfam14843
    Location:480 → 615
    GF_recep_IV; Growth factor receptor domain IV
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.