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TJP2 tight junction protein 2 [ Opisthocomus hoazin ]

Gene ID: 104338851, updated on 12-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Opisthocomus hoazin
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae; Opisthocomus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current ASM69207v1 (GCF_000692075.1) Unplaced Scaffold NW_009899513.1 (1728777..1781740, complement)

NW_009899513.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 19 member 1 Neighboring gene collagen type XVIII alpha 1 chain Neighboring gene frataxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009899513.1 Unplaced Scaffold Reference ASM69207v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Opisthocomus hoazin Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69207v1

Genomic

  1. NW_009899513.1 Reference ASM69207v1

    Range
    1728777..1781740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009944947.1 → XP_009943249.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (4) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. XM_009944939.1 → XP_009943241.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (4) summary
    cd12027
    Location:600 → 662
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:696 → 875
    GuKc; Guanylate kinase homologues
    smart00228
    Location:300 → 378
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
Heading Accession and Version

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