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CHEK2 checkpoint kinase 2 [ Dryobates pubescens (Downy woodpecker) ]

Gene ID: 104309009, updated on 12-Mar-2024

Summary

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Gene symbol
CHEK2
Gene description
checkpoint kinase 2
See related
EnsemblRapid:ENSPPUG00010002955
Gene type
protein coding
RefSeq status
MODEL
Organism
Dryobates pubescens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Piciformes; Picidae; Dryobates
Orthologs
human mouse all
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Genomic context

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See CHEK2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_03 current bDryPub1.pri (GCF_014839835.1) 25 NC_071636.1 (168194..178201)
100 previous assembly ASM69900v1 (GCF_000699005.1) Unplaced Scaffold NW_009661916.1 (1338709..1348221, complement)

Chromosome 25 - NC_071636.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2, facilitated glucose transporter member 11 Neighboring gene HscB mitochondrial iron-sulfur cluster cochaperone Neighboring gene coenzyme Q5, methyltransferase Neighboring gene dynein light chain 1, cytoplasmic

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase Chk2
Names
Serine/threonine-protein kinase Chk2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_014839835.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bDryPub1.pri

Genomic

  1. NC_071636.1 Reference bDryPub1.pri

    Range
    168194..178201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009910269.2 → XP_009908571.1  serine/threonine-protein kinase Chk2

    See identical proteins and their annotated locations for XP_009908571.1

    UniProtKB/TrEMBL
    A0A093G7P3
    Related
    ENSPPUP00010003025.1, ENSPPUT00010004542.1
    Conserved Domains (3) summary
    smart00220
    Location:197 → 463
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd00060
    Location:88 → 179
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd14084
    Location:190 → 463
    STKc_Chk2; Catalytic domain of the Serine/Threonine kinase, Cell cycle Checkpoint Kinase 2
Nucleotide Protein
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