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PLAT plasminogen activator, tissue type [ Gavia stellata (red-throated loon) ]

Gene ID: 104250455, updated on 12-Mar-2024

Summary

Gene symbol
PLAT
Gene description
plasminogen activator, tissue type
Locus tag
N328_10971
Gene type
protein coding
RefSeq status
MODEL
Organism
Gavia stellata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia
Orthologs
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Genomic context

Location:
chromosome: 31
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current bGavSte3.hap2 (GCF_030936135.1) 31 NC_082624.1 (6529782..6544192, complement)
100 previous assembly ASM69087v1 (GCF_000690875.1) Unplaced Scaffold NW_009290109.1 (7439..15811)

Chromosome 31 - NC_082624.1Genomic Context describing neighboring genes Neighboring gene lysine acetyltransferase 6A Neighboring gene adaptor related protein complex 3 subunit mu 2 Neighboring gene inhibitor of nuclear factor kappa B kinase subunit beta Neighboring gene voltage dependent anion channel 3 Neighboring gene DNA polymerase beta

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in plasminogen activation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in smooth muscle cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tissue-type plasminogen activator
Names
Tissue-type plasminogen activator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030936135.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGavSte3.hap2

Genomic

  1. NC_082624.1 Reference bGavSte3.hap2

    Range
    6529782..6544192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059831421.1XP_059687404.1  tissue-type plasminogen activator isoform X3

  2. XM_059831420.1XP_059687403.1  tissue-type plasminogen activator isoform X2

  3. XM_059831422.1XP_059687405.1  tissue-type plasminogen activator isoform X4

  4. XM_009807434.2XP_009805736.1  tissue-type plasminogen activator isoform X1

    Conserved Domains (4) summary
    smart00020
    Location:312552
    Tryp_SPc; Trypsin-like serine protease
    cd00108
    Location:125210
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:315555
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cl00063
    Location:4281
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...